Results 41 to 50 of about 26,266 (223)

Immunization with antigenic extracts of Leishmania associated with Montanide ISA 763 adjuvant induces partial protection in BALB/c mice against Leishmania (Leishmania) amazonensis infection [PDF]

, 2014
Background/Purpose: A proper adjuvant has a relevant role in vaccine formulations to generate an effective immune response. In this study, total Leishmania antigen (TLA) formulated with Montanide ISA 763 or R848 as adjuvants were evaluated as a first ...
Cargnelutti, Diego Esteban, Celedon, Verónica, Cuello Carrión, Fernando Darío, Garcia Bustos, Maria Fernanda, Morea, Gastón, Salomón, María Cristina, Scodeller, Eduardo   +6 more
core   +1 more source

Cytokines and chemokines measured in dried SLA-stimulated whole blood spots for asymptomatic Leishmania infantum and Leishmania donovani infection

Scientific Reports, 2017
AbstractWhole blood stimulation with soluble Leishmania antigen (SLA), followed by plasma cytokine and chemokine determination, provides means of detecting subjects with asymptomatic Leishmania infection. This work examines the potential of Protein Saver 903 cards for the storage and transport of SLA-stimulated dried plasma spot samples.
A. V. Ibarra-Meneses, D. Mondal, J. Alvar, J. Moreno, E. Carrillo   +4 more
openaire   +3 more sources

Effect of Antimonial Therapy on Levels of (TNF-α and IL-1β) Cytokines in Cutaneous Leishmaniasis Patients in Iraq

Nano Biomedicine and Engineering, 2019
This study aimed to study the effective antimonial therapy on circulating levels proinflammatory cytokines, and their effect on susceptibility to cutaneous leishmaniasis (CL) infection in the Iraqi population.
Hasan Raheem Khudhur, Ahmed Abbas Hasan, Rawaa Adday Ali   +2 more
doaj   +1 more source

Early suppression of lymphoproliferative response in dogs with natural infection by Leishmania infantum. [PDF]

, 1999
Dogs are the domestic reservoirs of zoonotic visceral leishmaniasis caused by Leishmania infantum. Early detection of canine infections evolving to clinically patent disease may be important to leishmaniasis control.
CIARAMELLA, PAOLO, DE LUNA R., GRADONI L., IELPO M. T. L. AMBROSIO R., MANCINO D., MOSCATIELLO V., PIANTEDOSI, DIEGO, SCALONE A., VUOTTO M. L.   +8 more
core   +1 more source

Aryl Hydrocarbon Receptor-Signaling Regulates Early Leishmania major-Induced Cytokine Expression

Frontiers in Immunology, 2019
The early inflammatory skin micromilieu affects resistance in experimental infection with Leishmania major. We pursue the concept that macrophages, which take up parasites during early infection, exert decisive influence on the inflammatory micromilieu ...
Niels-Arne Münck, Niels-Arne Münck, Johannes Roth, Cord Sunderkötter, Cord Sunderkötter, Cord Sunderkötter, Jan Ehrchen   +6 more
doaj   +1 more source

Parasite excretory-secretory products and their effects on metabolic syndrome [PDF]

, 2017
Obesity, one of the main causes of metabolic syndrome (MetS), is an increasingly common health and economic problem worldwide, and one of the major risk factors for developing type 2 diabetes and cardiovascular disease. Chronic, low-grade inflammation is
Crowe, J., Harnett, M.M., Harnett, W., Lumb, F.E.   +3 more
core   +2 more sources

Leishmania infantum amastigotes enhance HIV-1 production in cocultures of human dendritic cells and CD4 T cells by inducing secretion of IL-6 and TNF-alpha. [PDF]

PLoS Neglected Tropical Diseases, 2009
Visceral leishmaniasis has emerged as an important opportunistic disease among patients infected with HIV-1. Both HIV-1 and the protozoan parasite Leishmania can productively infect cells of the macrophage-dendritic cell lineage.Here we demonstrate that ...
Ravendra Garg, Corinne Barat, Michel Ouellet, Robert Lodge, Michel J Tremblay   +4 more
doaj   +1 more source

A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]

, 2018
This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho, Combes, Dlugonska, Hart, Ingrid Evans-Osses, Izadora Volpato Rossi, Jameel Inal, Kho, Lechartier, Marcel I. Ramirez, Nten, Zingales   +11 more
core   +2 more sources

Association of pro-inflammatory cytokines and iron regulatory protein 2 (IRP2) with Leishmania burden in canine visceral leishmaniasis. [PDF]

PLoS ONE, 2013
Leishmania infantum infection in humans and dogs can evolve with a wide range of clinical presentations, varying from asymptomatic infections to visceral leishmaniasis. We hypothesized that the immune response elicited by L.
Paulo Ricardo Porfírio do Nascimento, Daniella Regina Arantes Martins, Glória Regina Góis Monteiro, Paula Vivianne Queiroz, Francisco Paulo Freire-Neto, José Wilton Queiroz, Adila Lorena Morais Lima, Selma Maria Bezerra Jeronimo   +7 more
doaj   +1 more source

Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study [PDF]

, 2018
Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP).
A Mazeris, A Saha, A Sainz, AS De Tommasi, C Attipa, C Attipa, C Maia, CB Cardinot, CF Alves, Charalampos Attipa, Chris Helps, CL Barbieri, CLA Ehrlichiosis, D Chochlakis, D Otranto, D Otranto, David Morris, Francesca Soutter, G Baneth, G Baneth, J Alvar, J Franca-Costa, J Le Gal, J Moreno, K Katherine, Kostas Papasouliotis, L Cortese, L Cortese, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, M Novacco, M Olivier, M-D Tabar, MG Vrhovec, MJ Day, MJ Grigg, P Parola, P Seneviratna, R Killick-Kendrick, RB Kline, RJ Quinnell, RN Davidson, S Carver, S Davies, S Harrus, S Harrus, S Tasker, Scott Carver, SE Shaw, Séverine Tasker, T Bouzouraa, V Pintado, WH Pryor Jr, Y Mekuzas, Y Rosseel   +55 more
core   +5 more sources