Cytokinin signaling mediated by KMD2 promotes Arabidopsis hypocotyl grafting success. [PDF]
Kim J, Strader L, Damodaran S.
europepmc +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
The cytokinin histidine kinase receptors regulate nodulation, shoot and root development in <i>Pisum sativum</i>. [PDF]
Velandia K +11 more
europepmc +1 more source
Abstract Objective To highlight key factors required to optimize multi‐mechanistic approaches with oral combination treatments for the acute management of a migraine attack. Background Given the complex multi‐factorial nature of migraine, combining treatments with different mechanisms of action should improve outcomes compared to monotherapies, but ...
Stephen Silberstein, Alan M. Rapoport
wiley +1 more source
Identification of a cytokinin-responsive core promoter and interacting transcription factors of MtCKX1 in Medicago truncatula. [PDF]
Li Y +5 more
europepmc +1 more source
Supplementation of Driver and Kuniyuki Walnut Medium with phloroglucinol enhanced regeneration efficiency in tomato tissue culture. Heterologous expression of an Arabidopsis growth‐regulating factor gene, GROWTH‐REGULATING FACTOR5 (GRF5), in tomato improved regeneration and transformation efficiency, suggesting a synergistic effect between ...
Junjie Rong +6 more
wiley +1 more source
Differential activity of CYTOKININ OXIDASE/DEHYDROGENASE3 (CKX3) and CKX5 genes in regulating yield components in Brassica napus L. [PDF]
Schwarz I, Möllers C, Schmülling T.
europepmc +1 more source
Stem Cells in Cosmetic Applications: Advancements, Challenges, and Future Directions
ABSTRACT Background Biotechnology has significantly impacted the cosmetics industry, particularly through the incorporation of plant stem cells, which possess regenerative properties beneficial for skincare. Aims This review aims to evaluate the potential benefits and challenges of using plant stem cells in cosmetics, while discussing future directions
Farid KarkonShayan +4 more
wiley +1 more source
The Role of Endogenous Hormones in Regulating Early Development of Stone Fruit. [PDF]
Zhang S, Sun Y, Zhou X, Deng Z.
europepmc +1 more source
Scaling law links plant growth variation to grain yield in wheat stands
Summary Growth rate, a fundamental trait associated with plant resource use, scales with plant mass, following consistent allometric power laws shaped by biophysical constraints and natural selection captured in metabolic scaling theory (MST). Although well‐established in wild plants, MST has been overlooked in crop improvement.
Guy Golan +6 more
wiley +1 more source

