SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
EUS-FNA with ROSE for pancreatic solid lesions: a single-center experience. [PDF]
Lu Q +5 more
europepmc +1 more source
Committee II: Guidelines for cytologic sampling techniques of lung and mediastinal lymph nodes [PDF]
Claire W. Michael +8 more
openalex +1 more source
Finding More in Less: Precision Medicine for Pancreatic Cancer Using Residual Cytology Samples
The study evaluates the use of residual liquid‐based cytology (LBC) samples from pancreatic ductal adenocarcinoma (PDAC) for molecular analysis. It shows that LBC samples preserve nucleic acid quality and remain suitable for next‐generation sequencing (NGS) and MSI testing even after prolonged storage, underscoring their value when other samples are ...
Raquel Antón‐Peñalver +17 more
wiley +1 more source
The Usefulness of Extemporaneous Cytological Examination in Imaging-Guided Biopsies. [PDF]
Rubini A +8 more
europepmc +1 more source
CONJUNCTIVAL IMPRESSION CYTOLOGY (CIC)- TECHNIQUE AND INTERPRETATION
P Muralidharan +1 more
openalex +1 more source
Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller +2 more
wiley +1 more source
Abstract Aims Precision nutrition, guided by genetic testing, has emerged as a promising approach for managing obesity. However, robust clinical trials testing its effectiveness in real‐world dietary interventions remain scarce. The GenOn Programme aims to evaluate whether tailoring nutritional care based on genetic risk for obesity enhances weight ...
Karla P. Balbino +11 more
wiley +1 more source
Nasal cytology: Cornerstone and future directions in precision nasal disease management. [PDF]
Zhang Y, Zhang L.
europepmc +1 more source
Ongoing transmission of onchocerciasis in the Pru District of Ghana after two decades of mass drug administration with ivermectin and comparative identification of members of the Simulium damnosum complex using cytological and morphological techniques [PDF]
Friday Maduka Chikezie +5 more
openalex +1 more source

