Results 91 to 100 of about 13,763 (258)

Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A Streptococcus Survival in Macrophages [PDF]

, 2014
Group A Streptococcus (GAS, Streptococcus pyogenes) is an ongoing threat to human health as the agent of streptococcal pharyngitis, skin and soft tissue infections, and life-threatening conditions such as necrotizing fasciitis and streptococcal toxic ...
Bastiat-Sempe, Benedicte, Lomayesva, Natalie, Love, John F., Wessels, Michael R.   +3 more
core   +1 more source

Multiomics integration of 16S rRNA, metagenomic, and metabolomic analyses unveils gut microbiota–metabolite interactions in Guizhi Fuling capsule‐treated chronic pelvic inflammatory disease rats

Advanced Chinese Medicine, Volume 2, Issue 4, Page 163-177, December 2025.
Guizhi Fuling capsule likely alleviates chronic pelvic inflammatory disease by exerting anti‐inflammatory effects, restoring TCA cycle energy metabolism, reshaping gut microbiota structure, inhibiting quorum sensing signaling, and improving polysaccharide metabolic functions.
Hongli Chen, Mengyu Qian, Zhelong Feng, Xia Gao, Ruotong Huang, Yan Xie, Liang Cao, Xialin Chen, Wei Xiao   +8 more
wiley   +1 more source

The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa. [PDF]

PLoS ONE, 2009
BACKGROUND: The pathogenicity of the Vibrio cholerae strains belonging to serogroup O1 and O139 is due to the production of virulence factors such as cholera toxin (CT) and the toxin-coregulated pilus (TCP). The remaining serogroups, which mostly lack CT
Lucantonio Debellis, Anna Diana, Diletta Arcidiacono, Romina Fiorotto, Piero Portincasa, Donato Francesco Altomare, Carlo Spirlì, Marina de Bernard   +7 more
doaj   +1 more source

Identification of a target protein of Hydra actinoporin-like toxin-1 (HALT-1)using GST affinity purification and SILAC-based quantitative proteomics [PDF]

, 2017
Hydra actinoporin-like toxin-1 (HALT-1) is a 20.8 kDa pore-forming toxin isolated from Hydra magnipapillata. HALT-1 shares structural similarity with actinoporins, a family that is well known for its haemolytic and cytolytic activity.
Ameirika, ., Hong, Xi Sha, Hwang, Jung Shan *   +2 more
core   +1 more source

A Bioorthogonal and Programmable Bacterial Delivery System for Spatiotemporally Targeted Therapy of Solid Tumors

Exploration, Volume 5, Issue 6, December 2025.
We developed a spatiotemporal targeting oncolytic bacterial therapy system, the STEPT (spatiotemporal targeting EcN‐pfo terminator) system, which injects azide hyaluronic acid hydrogel into tumors to capture DBCO‐labeled engineered Escherichia coli Nissle 1917 (EcN).
Yu‐Jia Wang, Wen‐Jie Jiang, Hua‐Jun Zhao, Jian‐Qun Deng, Yi‐Min Cai, Yi Li, Xiao‐Lin Meng, Jin Hou, Feng‐Shan Wang, Ju‐Zheng Sheng   +9 more
wiley   +1 more source

The cytolytic capacity of Enterococcus faecalis isolates from cheese, yogurt, and curd [PDF]

Iraqi Journal of Veterinary Sciences
Food safety is an important issue that concerns scientific and commercial communities worldwide for its direct impact on people’s health. The current study used conventional methods to isolate Enterococcus faecalis from dairy products.
Wisam R. Atiyah, Orooba M Faja, Qasim Z. Bneed, Ziad M. Al-khozai   +3 more
doaj   +1 more source

Food Safety Threats: Molecular Surveillance, Antibiogram and Virulence Profiling of Biofilm Forming Enterococcus faecalis in Bangladeshi Restaurants

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Nowadays, researchers have found Enterococci in many food items. E. faecalis prevalence, antimicrobial resistance, pathogenicity, and biofilm‐forming capacity in food samples and food outlets in Bangladesh are little known. Microbiological conditions in food preparation sectors must be examined to ensure food safety and meet optimum criteria for high ...
Saad As Shadique, Farhana Binte Ferdous, Md. Nahid Ashraf, Sabrina Sultana Rimi, Mohosin Kabir, Md. Tanvir Rahman, Md. Shafiqul Islam   +6 more
wiley   +1 more source

Hemolytic toxin from the soft coral Sarcophyton trocheliophorum: isolation and physiological characterization

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
The unifying characteristic of cnidarians is the production of protein and polypeptide toxins. The present study describes the identification of a hemolytic toxin from the soft coral Sarcophyton trocheliophorum.
S Karthikayalu, V Rama, R Kirubagaran, R Venkatesan   +3 more
doaj  

Insights from the draft genome into the pathogenicity of a clinical isolate of Elizabethkingia meningoseptica Em3

Standards in Genomic Sciences, 2017
Elizabethkingia meningoseptica is an emerging, healthcare-associated pathogen causing a high mortality rate in immunocompromised patients. We report the draft genome sequence of E.
Shicheng Chen, Marty Soehnlen, Frances P. Downes, Edward D. Walker   +3 more
doaj   +1 more source

Pneumolysin Activates Macrophage Lysosomal Membrane Permeabilization and Executes Apoptosis by Distinct Mechanisms without Membrane Pore Formation [PDF]

, 2014
Intracellular killing of Streptococcus pneumoniae is complemented by induction of macrophage apoptosis. Here, we show that the toxin pneumolysin (PLY) contributes both to lysosomal/phagolysosomal membrane permeabilization (LMP), an upstream event ...
Albiger, Ali, Alouf, Baba, Berry, Beurg, Bewley, Bewley, Bidère, Bouvier, Braun, Braun, Brown, Brueggemann, Canvin, Clark, Cockeran, Craven, Daigneault, Dela Cruz, Dockrell, Dockrell, Fang, Gilbert, Gillespie, Gordon, Harder, Hornung, Houldsworth, Ip, Jefferies, Johansson, Kadioglu, Kadioglu, Kagan, Kemp, Kirkham, Knapp, Knapp, Koga, Kurz, Littmann, Madden, Malley, Marriott, Marriott, Marriott, McComb, McNeela, Meixenberger, Mitchell, Mitchell, Montgomery, Muñoz-Planillo, Opitz, Ortqvist, Qi, Rajput, Ratner, Rossjohn, Rubins, Sabroe, Schmeck, Schmeck, Srivastava, Talstad, Thiele, Tilley, Turk, Uchimoto, Witsell, Witzenrath, Yuste   +72 more
core   +2 more sources