Results 101 to 110 of about 13,763 (258)
Microbiology SpectrumSpecific elimination of cytolytic Enterococcus faecalis from the intestinal microbiota by bacteriophages (phages) attenuates ethanol-induced liver disease in pre-clinical studies; however, other clinical phage therapy studies have reported the occurrence
Jumpei Fujiki +5 more
doaj +1 more source
Pneumolysin: Pathogenesis and Therapeutic Target
Frontiers in Microbiology, 2020 Streptococcus pneumoniae is an opportunistic pathogen responsible for widespread illness and is a major global health issue for children, the elderly, and the immunocompromised population.
Andrew T. Nishimoto +2 more
doaj +1 more source
Engineering Bacteria as Living Therapeutics in Cancer Therapy
Advanced Science, Volume 12, Issue 42, November 13, 2025.Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen +6 more
wiley +1 more source
The Gut‒Liver Axis in Liver Disease: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 6, Issue 11, November 2025.The global burden of liver disease is increasing, and gut‐liver axis dysregulation is a key driver. This article explains its mechanisms in various liver diseases and explores targeted therapeutic strategies, aiming to provide new insights into liver disease treatment.
Zhiji Chen +11 more
wiley +1 more source
Bacterial pore-forming toxins: The (w)hole story? [PDF]
, 2018 .: Pore-forming toxins (PFTs) are the most common class of bacterial protein toxins and constitute important bacterial virulence factors. The mode of action of PFT is starting to be better understood.
Bischofberger, M. +4 more
core
Clostridium perfringens strains from bovine enterotoxemia cases are not superior in in vitro production of alpha toxin, perfringolysin O and proteolytic enzymes [PDF]
, 2014 Background: Bovine enterotoxemia is a major cause of mortality in veal calves. Predominantly veal calves of beef cattle breeds are affected and losses due to enterotoxemia may account for up to 20% of total mortality.
Deprez, Piet +8 more
core +2 more sources
A Cas12a Toolbox for Rapid and Flexible Group B Streptococcus Genomic Editing and CRISPRi
Molecular Microbiology, Volume 124, Issue 5, Page 449-461, November 2025.We developed a resource set and protocols that allow researchers to quickly alter or silence genes in Group B Streptococcus. Using flexible plasmids and a drug‐inducible Cas12a system, the approach enables efficient generation of insertions, deletions, or knockdowns. These tools are publicly available.
G. H. Hillebrand +5 more
wiley +1 more source
Advanced Materials Interfaces, Volume 12, Issue 20, October 27, 2025.Supported lipid bilayers coupled with multielectrode array devices offer significant promise for pathogen–host cell membrane interaction studies. This work demonstrates, for the first time, the compatibility of this platform with biological fluids, in this case whole human blood, essential for any future point‐of‐care applications; as well as its ...
Alexandra Wheeler +4 more
wiley +1 more source
Genotyping and antimicrobial resistance patterns of Escherichia coli O157 originating from cattle farms [PDF]
, 2011 During a Escherichia coli O157 prevalence study on cattle farms, 324 E. coli O157 isolates were collected from 68 out of 180 cattle farms. All isolates harbored the eaeA gene and the enterohemolysin (ehxA) gene. The majority of the strains only contained
Boyen, Filip +4 more
core +1 more source
Brazilian Dental Science, 2014 Objective: More virulent strains may result from the acquisition of genes by genetic exchange, pathogenicity islands in several species encoding toxins, adhesion factors and other factors associated with virulence.
Ana Claudia C. Xavier +3 more
doaj +1 more source