Journal of Neuroinflammation, 2019 Background Streptococcus pneumoniae is the cause of a highly lethal form of meningitis in humans. Microglial cells in the brain represent the first line of defense against pathogens, and they participate in the inflammatory response.
Sabrina Hupp +5 more
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Functional classification of protein toxins as a basis for bioinformatic screening [PDF]
, 2017 Proteins are fundamental to life and exhibit a wide diversity of activities, some of which are toxic. Therefore, assessing whether a specific protein is safe for consumption in foods and feeds is critical.
Braun, Werner +11 more
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Vaginal hydrolytic enzymes, immunoglobulin A against Gardnerella vaginalis toxin, and risk of early preterm birth among women in preterm labor with bacterial vaginosis or intermediate flora [PDF]
, 2002 Objective: The purpose of this study was to determine whether the microbial hydrolytic enzymes, sialidase and prolidase, and immunoglobulin A against the Gardnerella vaginalis cytolysin (anti-Gvh IgA) increase the risk for early preterm birth ( 6434 ...
Agnew, K +6 more
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Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin
Frontiers in Immunology, 2012 The cholesterol-dependent cytolysins (CDCs) attack cells by punching large holes in their membranes. Lectinolysin from Streptococcus mitis is unique among CDCs due to the presence of an N-terminal lectin domain that enhances the pore-forming activity of ...
Sara eLawrence +8 more
doaj +1 more source
Virulence factors in vancomycin-resistant and vancomycin- susceptible Enterococcus faecalis from Brazil [PDF]
, 2014 Enterococci are members of commensal flora of animals and insects, but are also important opportunistic pathogens. Our objective was to observe if there was any difference of virulence in several groups of E. faecalis, mainly between vancomycin-resistant
Camargo, I. L. B. C. +3 more
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Inhibiting mevalonate pathway enzymes increases stromal cell resilience to a cholesterol-dependent cytolysin [PDF]
, 2017 Animal health depends on the ability of immune cells to kill invading pathogens, and on the resilience of tissues to tolerate the presence of pathogens.
A Baxter +46 more
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Signaling beyond Punching Holes: Modulation of Cellular Responses by Vibrio cholerae Cytolysin
Toxins, 2015 Pore-forming toxins (PFTs) are a distinct class of membrane-damaging cytolytic proteins that contribute significantly towards the virulence processes employed by various pathogenic bacteria.
Barkha Khilwani, Kausik Chattopadhyay
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Purification and characterization of an extracellular cytolysin produced by Vibrio vulnificus [PDF]
, 1985 L D Gray, Arnold S. Kreger
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Infeksi Saluran Kemih Sebagai Faktor Risiko Terjadinya Ancaman Persalinan Preterm [PDF]
, 2015 Tujuan: Mengidentifikasi kuman penyebab infeksi saluran kemih sebagai faktor risiko terjadinya ancaman persalinan preterm.Bahan dan Metode: Penelitian ini adalah penelitian analitik observasional cross sectional, dilakukan di Kamar Bersalin dan Poli ...
Hardianto, G. (Gatut) +3 more
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Molecular Dynamics Simulations Reveal the Role of Membrane Cholesterol during Pore Forming Pathway of Cytolysin A [PDF]
, 2018 Amit K. Behera, K. G. Ayappa
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