Results 21 to 30 of about 13,763 (258)
Molecular Analysis of Bacterial Cytolysins [PDF]
Clinical Infectious Diseases, 1987 Results of molecular and pathogenic studies of three different bacterial hemolysins (cytolysins) are presented. These exoproteins derive from the two gram-negative bacteria Escherichia coli and Aeromonas hydrophila and from the gram-positive pathogen Listeria monocytogenes. The hemolysin of E.
Chakraborty, Trinad +7 more
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Pulmonary damage by Vibrio vulnificus cytolysin [PDF]
Infection and Immunity, 1996 Vibrio vulnificus is an estuarine bacterium that causes septicemia and serious wound infection. Cytolysin produced by V. vulnificus has been incriminated as one of the important virulence determinants of bacterial infection. Cytolysin (8 hemolytic units) given intravenously to mice via their tail veins caused severe hemoconcentration and lethality ...
Jin-Woo Park +8 more
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Cholesterol‐dependent cytolysins: The outstanding questions
IUBMB Life, 2022 AbstractThe cholesterol‐dependent cytolysins (CDCs) are a major family of bacterial pore‐forming proteins secreted as virulence factors by Gram‐positive bacterial species. CDCs are produced as soluble, monomeric proteins that bind specifically to cholesterol‐rich membranes, where they oligomerize into ring‐shaped pores of more than 30 monomers ...
Bronte A. Johnstone +8 more
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Spatiotemporal Regulation of Vibrio Exotoxins by HlyU and Other Transcriptional Regulators
Toxins, 2020 After invading a host, bacterial pathogens secrete diverse protein toxins to disrupt host defense systems. To ensure successful infection, however, pathogens must precisely regulate the expression of those exotoxins because uncontrolled toxin production ...
Byoung Sik Kim
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Microbiology Spectrum, 2022 Pore-forming toxins (PFTs) are commonly produced by pathogenic bacteria, and understanding them is key to the development of virulence-targeted therapies. Streptococcus agalactiae, or group B Streptococcus (GBS), produces several factors that enhance its
Ifrah Shahi +4 more
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Вестник войск РХБ защиты, 2023 Sea anemones are well-spread everywhere in the World Ocean and represent the most ancient active poisonous organisms. Their main instrument of attack on other animals are the nematocysts – stinging organelles with the curtailed hollow thread with ...
R. S. Kalina, M. M. Monastyrnaya
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Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications. [PDF]
FASEB JThis review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Dai E +5 more
europepmc +2 more sources
The Role of Selected Virulence Factors in Infections Caused by Enterococcus spp.
Postępy Mikrobiologii, 2023 Ziarenkowce z rodzaju Enterococcus spp. są składnikiem mikrobioty ludzi i zwierząt oraz powszechnie występują w środowisku naturalnym. Należą do patogenów warunkowo chorobotwórczych, mogących wywoływać zakażenia o różnej lokalizacji.
Kraszewska Zuzanna +3 more
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The crystal structure of Pneumolysin at 2.0 Å resolution reveals the molecular packing of the pre-pore complex [PDF]
, 2015 Pneumolysin is a cholesterol-dependent cytolysin (CDC) and virulence factor of Streptococcus pneumoniae. It kills cells by forming pores assembled from oligomeric rings in cholesterol-containing membranes.
Andrew, Peter W +8 more
core +1 more source
Toxins, 2021 Actinoporins (APs) are soluble pore-forming proteins secreted by sea anemones that experience conformational changes originating in pores in the membranes that can lead to cell death. The processes involved in the binding and pore-formation of members of
Carlos Alvarez +8 more
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