Results 41 to 50 of about 13,763 (258)

Cytolysins of Actinobacillus pleuropneumoniae serotype 9 [PDF]

Infection and Immunity, 1991
Cytolysin I (ClyI) and cytolysin II (ClyII), which are present in the culture supernatant of Actinobacillus pleuropneumoniae serotype 9, are thought to play an important role in the pathogenesis of pig pleuropneumonia. The purpose of this study was to clone and characterize the genetic determinants of these cytolysins.
M A, Smits, J, Briaire, R, Jansen, H E, Smith, E M, Kamp, A L, Gielkens   +5 more
openaire   +2 more sources

Repair of a Bacterial Small β-Barrel Toxin Pore Depends on Channel Width

mBio, 2017
Membrane repair emerges as an innate defense protecting target cells against bacterial pore-forming toxins. Here, we report the first paradigm of Ca2+-dependent repair following attack by a small β-pore-forming toxin, namely, plasmid-encoded phobalysin ...
Gisela von Hoven, Amable J. Rivas, Claudia Neukirch, Martina Meyenburg, Qianqian Qin, Sapun Parekh, Nadja Hellmann, Matthias Husmann   +7 more
doaj   +1 more source

Phenotypic and genotypic characteristics of enterocin producing enterococci against pathogenic bacteria [PDF]

Macedonian Veterinary Review, 2015
The study investigated the antimicrobial activity of 13 enterococcal strains (E. faecalis -8, E. faecium-2, E. hirae-2, E. spp.-1) isolated from our traditional cheeses against pathogen microorganisms.
Sandra Mojsova, Kiril Krstevski, Igor Dzadzovski, Zagorka Popova, Pavle Sekulovski   +4 more
doaj   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A., Chain, B., Deretic, V., Dockrell, D.H., Francis, S.E., Kroemer, G., Marriott, H.M., Mitchell, T.J., Read, R.C., Tulone, C., Whyte, M.K.B.   +10 more
core   +5 more sources

Laboratory evaluation on pathogenic potentialities of Vibrio furnissii

Memorias do Instituto Oswaldo Cruz, 1993
Sixteen strains of Vibrio furnissii recovered from 16 Brazilian patients with diarrhea were screened for virulence-associated factors. All strains were non-invasive, non-fimbriated, and did not produce either enterotoxins or cholera-like toxin.
Vera Magalhães, Adauto Castello Filho, Macelo Magalhães, Tania T. Gomes   +3 more
doaj   +1 more source

Immune Response of an Oral Enterococcus faecalis Phage Cocktail in a Mouse Model of Ethanol-Induced Liver Disease

Viruses, 2022
Cytolysin-positive Enterococcus faecalis (E. faecalis) cause more severe alcohol-associated hepatitis, and phages might be used to specifically target these bacteria in a clinical trial. Using a humanized mouse model of ethanol-induced liver disease, the
Beatriz Garcia Mendes, Yi Duan, Bernd Schnabl   +2 more
doaj   +1 more source

Purification of a 19-kDa pore-forming cytolysin from the sea anemone Heteractis magnifica

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Pore-forming cytolysins of 19 kDa from sea anemones present a remarkable cytolytic property. In the present work, a purified 19-kDa cytolysin was obtained from the sea anemone Heteractis magnifica.
S Karthikayalu, V Rama, R Venkatesan
doaj   +1 more source

Isoprenoids increase bovine endometrial stromal cell tolerance to the cholesterol-dependent cytolysin from Trueperella pyogenes† [PDF]

, 2018
Preventing postpartum uterine disease depends on the ability of endometrial cells to tolerate the presence of the bacteria that invade the uterus after parturition.
Amos, Ayres, Bergstrom, Bergstrom, Bicalho, Billington, Bloch, Bonnett, Bustin, Christian, Cronin, Forman, Fukuchi, Gan, Gareth D Healey, Goldstein, Goldstein, Gonzalez, Griffin, Gurcel, Hardie, Healy, Hiyoshi, Huffman, I Martin Sheldon, Jost, Kalaany, Karstrup, Keller, Lange, LeBlanc, LeBlanc, Liao, Maxfield, McCusker, Mihaylova, Moore, Morgan, Mosmann, Park, Peraro, Preta, Preta, Read, Repa, Schneider, Sharpe, Sheldon, Sheldon, Sholeem Griffin, Statt, Turner, Turner, Tweten, Vander Heiden, Wang, Wathes, Westermann, Zoncu, Zwald   +59 more
core   +1 more source

Low incidence of cytolysin-positive E. faecalis and no correlation to survival in Danish patients with alcohol-associated hepatitis: A prospective cohort study

Gut Microbes Reports
Alcohol-associated hepatitis (AH) is a severe and life-threatening form of alcohol-associated liver disease with no approved treatments for reducing long-term mortality. Cytolysin-producing E.
Frederik Cold, Julie Elm Heintz, Khaled Saoud Ali Ghathian, Poul Als Stenbøg, Lars Hestbjerg Hansen, Alexander Byth Carstens, Andreas Munk Petersen, Sofie Ingdam Halkjaer, Flemming Bendtsen, Henriette Ytting   +9 more
doaj   +1 more source

Dual functions of discoidinolysin, a cholesterol-dependent cytolysin with N-terminal discoidin domain produced from Streptococcus mitis strain Nm-76

Journal of Oral Microbiology, 2022
Background Some strains of Streptococcus mitis exhibit β-hemolysis due to the β-hemolytic activity of cholesterol-dependent cytolysin (CDC). Recently, a gene encoding an atypical lectinolysin-related CDC was found in S. mitis strain Nm-76.
Atsushi Tabata, Airi Matsumoto, Ai Fujimoto, Kazuto Ohkura, Takuya Ikeda, Hiroki Oda, Shuto Yokohata, Miho Kobayashi, Toshifumi Tomoyasu, Ayuko Takao, Hisashi Ohkuni, Hideaki Nagamune   +11 more
doaj   +1 more source