Results 71 to 80 of about 13,763 (258)
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, EarlyView.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Toxins, 2015 Gardnerella vaginalis produces cytolysin vaginolysin (VLY), which has been suggested to be a contributor to bacterial vaginosis pathogenesis. VLY along with intermedilysin (ILY) from Streptococcus intermedius have been attributed to a group of ...
Milda Zilnyte +3 more
doaj +1 more source
Genomic and phenotypic diversity of Enterococcus faecalis isolated from endophthalmitis.
PLoS ONE, 2021 Enterococcus faecalis are hospital-associated opportunistic pathogens and also causative agents of post-operative endophthalmitis. Patients with enterococcal endophthalmitis often have poor visual outcomes, despite appropriate antibiotic therapy. Here we
Gayatri Shankar Chilambi +7 more
doaj +1 more source
Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins [PDF]
, 2018 Permeabilization of the plasma membrane represents an important threat for any cell, since it compromises its viability by disrupting cell homeostasis.
Etxaniz Iriondo, Asier +3 more
core +2 more sources
Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.Bacteriocinogenic Staphylococcus epidermidis ST0409KOC was isolated from cheese and characterized as bacteriocin‐producing with strong activity versus Listeria monocytogenes and other pathogens. S. epidermidis ST0409KOC can be considered a safe strain regarding its virulence genetic background, presenting only a single virulence gene of IS257 among the
Kayque Ordonho Carneiro +2 more
wiley +1 more source
PLoS Pathogens, 2013 Streptococcus pneumoniae (pneumococcal) meningitis is a common bacterial infection of the brain. The cholesterol-dependent cytolysin pneumolysin represents a key factor, determining the neuropathogenic potential of the pneumococci.
Carolin Wippel +10 more
doaj +1 more source
Pore‐forming cytolysins of Gram‐negative bacteria [PDF]
Molecular Microbiology, 1991 SummaryA great deal is known about the structure, function and metabolic effects of enzymatic bacterial toxins such as the diphtheria, pertussis and cholera toxins. By comparison, our understanding of the pore‐forming, cytolytic toxins, particularly those produced by Gram‐negative bacterial pathogens, is far less complete. The genetics and biochemistry
openaire +2 more sources
A Cellular Metalloproteinase Activates Vibrio cholerae Pro-cytolysin [PDF]
Journal of Biological Chemistry, 2004 Many strains of Vibrio cholerae produce a cytolysin (VCC) that forms oligomeric transmembrane pores in animal cells. The molecule is secreted as a procytolysin (pro-VCC) of 79 kDa that must be cleaved at the N terminus to generate the active 65-kDa toxin.
Angela, Valeva +8 more
openaire +2 more sources
Journal of Integrative Plant Biology, Volume 68, Issue 1, Page 39-56, January 2026.The fungal strain Trichoderma nigricans T32781 improved yield and reduced the grain cadmium concentrations of wheat and barley in cadmium‐polluted soils through microbial and metabolic interactions, offering a potential strategy for enhancing crop productivity and food safety in cadmium‐contaminated fields.
Shuo Zhang +9 more
wiley +1 more source
Antibody-based detection and inhibition of vaginolysin, the Gardnerella vaginalis cytolysin. [PDF]
PLoS ONE, 2009 Bacterial vaginosis (BV) is the most common vaginal infection worldwide and is associated with significant adverse sequelae. We have recently characterized vaginolysin (VLY), the human-specific cytotoxin produced by Gardnerella vaginalis and believed to ...
Tara M Randis +3 more
doaj +1 more source