Results 101 to 110 of about 101,747 (197)

DLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive Autophagy

Aging Cell, EarlyView.
In normal physiological processes, autophagy acts as a protective factor against aging stress. With the stress increase, the DLK/JNK3 pathway is activated and autophagy is continuously upregulated. In our study, excessive autophagy leads to hair cell senescence, which reveals that excessive autophagy can play a harmful role in senescence under certain ...
Rui Ding, Weiyi Huang, Chenling Shen, Yi Pan, Yiming Zhong, Bing Kong, Yilin Shen, Mingliang Xiang, Bin Ye   +8 more
wiley   +1 more source

Emerging Prognostic and Predictive Biomarkers for Human Cytomegalovirus Infection During Pregnancy: Unmet Needs and Future Perspectives. [PDF]

Viruses
Rotundo S, Tassone MT, Lionello R, Fusco P, Serapide F, Russo A.   +5 more
europepmc   +1 more source

Physical Activity Modifies the Metabolic Profile of CD4+ and CD8+ T‐Cell Subtypes at Rest and Upon Activation in Older Adults

Aging Cell, EarlyView.
The figure combines the effects of aging and physical activity on different T‐cell subsets. Overall, our data provide evidence of higher energy demand, impaired metabolic flexibility, and hyperinflammatory responses in aged T cells, and PA reduces metabolic demand in these cells, potentially through increased MD and improved metabolic flexibility ...
Jon Hazeldine, Edward Withnall, Alba Llibre, Niharika A. Duggal, Janet M. Lord, Amanda V. Sardeli   +5 more
wiley   +1 more source

Human cytomegalovirus infection induces L1 expression through UL38-dependent mTOR-KAP1 pathway. [PDF]

PLoS One
Park S, Jeong J, Ahn K.
europepmc   +1 more source

A 2‐Min Cytomegalovirus (CMV) Awareness Video Improves Pregnant Women's Knowledge and Planned Adherence to Hygiene Precautions

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Introduction Congenital cytomegalovirus (cCMV) is a leading infectious cause of life‐long neurodevelopmental disabilities, but public awareness of CMV is low. This study evaluated a short educational video on cCMV for its acceptability and impact on pregnant women's knowledge and planned hygiene adherence.
Tanya Tripathi, Jotara Watson, Hayley Smithers‐Sheedy, Kath Swinburn, Natalia Rode, Emma Waight, Annabel Webb, Natasha E. Holmes, Hanako Stump, Antonia Shand, Lisa Hui   +10 more
wiley   +1 more source

Auditory and Vestibular Involvement in Congenital Cytomegalovirus Infection. [PDF]

Pathogens
Pinninti SG, Britt WJ, Boppana SB.
europepmc   +1 more source

A case of visceral leishmaniasis mimicking connective tissue disease

Rheumatology &Autoimmunity, EarlyView.
Yucui Li, Hongxia Yang, Tingzi Zhao, Ke Xu, Liyun Zhang   +4 more
wiley   +1 more source

Endotypes in Immune Mediated Drug Reactions: Present and Future of Relevant Biomarkers. An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga, R. Fernandez‐Santamaria, G. E. Çelik, M. Labella, G. Murdaca, M. Sokolowska, D. Naisbitt, V. Sabato   +7 more
wiley   +1 more source

Correction to "Agreement Between Dried Blood Spot and Plasma PCR in Infants With Congenital Cytomegalovirus Infection". [PDF]

J Med Virol
europepmc   +1 more source

Is Neonatal Viremia a Possible Predictor of the Timing of Maternal Infection in Asymptomatic Congenital Cytomegalovirus Infection? A Retrospective Study. [PDF]

J Pers Med
Natale F, Boscarino G, Liuzzi G, Bonci F, Albanese GM, Cellitti R, Giancotti A, Franco F, Caravale B, Turchetta R, Turriziani O, Conti MG, Terrin G.   +12 more
europepmc   +1 more source