Results 131 to 140 of about 3,451,157 (398)

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Molecular characterization of viruses associated with gastrointestinal infection in HIV-positive patients

Brazilian Journal of Infectious Diseases
BACKGROUND: Diarrhea is a major cause of morbidity and mortality among HIV-infected patients worldwide. OBJECTIVE: We sought to determine the frequency of viral gastrointestinal infections among Brazilian HIV-infected patients with diarrhea.
Raquel C Silva, Fabrício J Benati, Giselle PA Pena, Norma Santos   +3 more
doaj   +1 more source

Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. [PDF]

, 2018
On September 22, 2008, a physician on Prince of Wales Island, Alaska, notified the Alaska Department of Health and Social Services (ADHSS) of an unusually high number of adult patients with recently diagnosed pneumonia (n = 10), including three persons ...
Barnard, Dale L, Beadle, James R, Hostetler, Karl Y, Kumaki, Yohichi, Mclean, Tyler Z, Roth, Jason P, Smee, Donald F, Valiaeva, Nadejda, Woolcott, John D   +8 more
core  

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

The problem of congenital cytomegalovirus infection

Журнал инфектологии, 2016
This paper comprises a review of up-to-date literature devoted to the problem of congenital cytomegalovirus infection, its epidemiology and pathogenesis.
R. A. Ivanova, V. V. Vasiliev, S. M. Vikhnina, M. Yu. Boboshko, G. M. Ushakova   +4 more
doaj  

A hidden menace? Cytomegalovirus infection is associated with reduced cortical gray matter volume in major depressive disorder

, 2020
Haixia Zheng, Bart N. Ford, Maurizio Bergamino, Rayus Kuplicki, Robin L. Aupperle, Jerzy Bodurka, Yoon‐Hee Cha, Justin S. Feinstein, Sahib S. Khalsa, Martin P. Paulus, Jonathan Savitz, Teresa A. Victor, Peter W. Hunt, Jerzy Bodurka, T. Kent Teague, Michael R. Irwin, Robert H. Yolken, Martin P. Paulus, Jonathan Savitz, Jonathan Savitz   +19 more
openalex   +2 more sources

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Cytomegalovirus infections: therapeutic potential in pregnancy [PDF]

Гинекология, 2014
The article presents the results of simultaneous clinical multicenter controlled study of comparative assessment of therapeutic efficacy, safety and tolerability Panavir, solution for intravenous injection of 0,04 mg/ml with the Standardl human ...
V N Prilepskaya, A V Ledina, N A Korotkova   +2 more
doaj  

AIDS-Associated Cytomegalovirus Infection of the Submandibular Gland Mimicking a Tumour [PDF]

, 1994
David Schellenberg, N Desmond, Siobhán Murphy, A G Tanner   +3 more
openalex   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source