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Chinese Clinical Practice Guidelines for Auditory Neuropathy (gCAN)
ABSTRACT Auditory neuropathy (AN) is an auditory disorder that affects the function of the auditory pathway. An increasing number of AN cases have been identified with the revelation of the underlying mechanisms, the advancements of diagnostic and detecting techniques.
Chinese Multi‐Center Research Collaborative Group on Clinical Diagnosis and Intervention of Auditory Neuropathy; Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Society of Otorhinolaryngology Head and Neck Surgery+43 more
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Cucurbit aphid‐borne yellows virus: A growing but overlooked threat to global cucurbit production
Cucurbit aphid‐borne yellows virus (CABYV) presents a significant threat to cucurbit crops worldwide. In this description of a plant virus we review what is currently known about this plant virus. Abstract Cucurbit aphid‐borne yellows virus (CABYV) presents a significant threat to cucurbit crops worldwide.
M. P. Rabadán+2 more
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Do stylet‐borne aphid‐transmitted viruses share the same binding sites?
Here, we tested if different stylet‐borne aphid‐transmitted viruses can compete for the same binding sites within the aphid stylets. We conducted sequential transmission assays of a potyvirus (ZYMV) followed by a cucumovirus (CMV) using Aphis gossypii as a vector and melon and pepper as test plants.
Rocío Galán‐Cubero+11 more
wiley +1 more source
DLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive Autophagy
In normal physiological processes, autophagy acts as a protective factor against aging stress. With the stress increase, the DLK/JNK3 pathway is activated and autophagy is continuously upregulated. In our study, excessive autophagy leads to hair cell senescence, which reveals that excessive autophagy can play a harmful role in senescence under certain ...
Rui Ding+8 more
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Pre‐Vaccination Immunotypes and Immune Entropy Are Indicators of Multiple Vaccine Responsiveness
Pre‐vaccination immune profiles and a novel biomarker, immune entropy, are associated with responsiveness to influenza, pneumococcal, and SARS‐CoV‐2 vaccines, independent of age, sex, and CMV serostatus, and also correlate with inflammaging‐related serum proteins, supporting their potential as indicators of immunosenescence validated across diverse ...
Alper Cevirgel+14 more
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A case of visceral leishmaniasis mimicking connective tissue disease
Rheumatology &Autoimmunity, EarlyView.
Yucui Li+4 more
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Healthy RPE cells produce AMPs and AMP precursors, including amyloid precursor protein (APP) and chemerin, and protect the neuroretina from blood‐borne pathogens and maintain homeostasis. When RPE cells undergo senescence, the antibacterial activity declines, and APP undergoes amylogenesis, leading to Aβ deposition.
Jian Liu+7 more
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ABSTRACT Introduction Congenital cytomegalovirus (cCMV) is a leading infectious cause of life‐long neurodevelopmental disabilities, but public awareness of CMV is low. This study evaluated a short educational video on cCMV for its acceptability and impact on pregnant women's knowledge and planned hygiene adherence.
Tanya Tripathi+10 more
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RSV infection induces lasting epigenetic and transcriptional changes in LECs, upregulating MHC‐I and MHC‐II, further amplified by LPS exposure. This is accompanied by increased antigen uptake, processing, and presentation. These persistent alterations may influence immune responses, potentially impacting both immunity to infection and respiratory ...
Piotr P. Janas+11 more
wiley +1 more source