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Seminars in Pediatric Neurology, 2012
Human cytomegalovirus, a human herpesvirus, remains a major cause of neurological disorders as a consequence of infections acquired in utero or postnatally. This article summarizes current information regarding the epidemiology, clinical manifestations, treatment, and prevention of this ubiquitous human infection.
J. Bale
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Human cytomegalovirus, a human herpesvirus, remains a major cause of neurological disorders as a consequence of infections acquired in utero or postnatally. This article summarizes current information regarding the epidemiology, clinical manifestations, treatment, and prevention of this ubiquitous human infection.
J. Bale
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Infections at the maternal–fetal interface: an overview of pathogenesis and defence
Nature Reviews Microbiology, 2021 Infections are a major threat to human reproductive health, and infections in pregnancy can cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to congenital infection and severe disease.
Christina J Megli, Carolyn B Coyne
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Congenital cytomegalovirus infection
BMJ, 2021### What you need to know Congenital cytomegalovirus (cCMV) infection is a common congenital infection, affecting one in every 100-200 live births globally.1 Long term neurodevelopmental sequelae occur in a quarter of children affected. This article provides a clinical update of the literature on the prevention, diagnosis, treatment, and anticipatory ...
Megan H Pesch +4 more
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Clinics in Chest Medicine, 1988
The pathogenic importance of cytomegalovirus (CMV) infection in AIDS-associated pneumonitis is controversial. Uncertainty regarding the significance of CMV isolation from pulmonary secretions of AIDS patients results in part from the difficulty in distinguishing CMV infection from CMV disease and from the high frequency of pulmonary CMV co-infection ...
M A, Jacobson, J, Mills
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The pathogenic importance of cytomegalovirus (CMV) infection in AIDS-associated pneumonitis is controversial. Uncertainty regarding the significance of CMV isolation from pulmonary secretions of AIDS patients results in part from the difficulty in distinguishing CMV infection from CMV disease and from the high frequency of pulmonary CMV co-infection ...
M A, Jacobson, J, Mills
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Pediatrics In Review, 2012
Although commonly asymptomatic, congenital CMV infection is the leading cause of nonhereditary SNHL. Other sequelae that may be evident only after the neonatal period can include chorioretinitis, neurodevelopmental delay with mental or motor impairment, and microcephaly.
Erin J, Plosa +3 more
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Although commonly asymptomatic, congenital CMV infection is the leading cause of nonhereditary SNHL. Other sequelae that may be evident only after the neonatal period can include chorioretinitis, neurodevelopmental delay with mental or motor impairment, and microcephaly.
Erin J, Plosa +3 more
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Seminars in Perinatology, 1998
Cytomegalovirus (CMV) infection is the most common perinatal infection and may result in severe injury to the fetus. Forty percent to 50% of infants delivered to mothers with primary CMV will have congenital infections. Of these, 5% to 18% will be overtly symptomatic at birth. The mortality rate in these children is almost 30%; approximately 80% of the
H L, Brown, M P, Abernathy
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Cytomegalovirus (CMV) infection is the most common perinatal infection and may result in severe injury to the fetus. Forty percent to 50% of infants delivered to mothers with primary CMV will have congenital infections. Of these, 5% to 18% will be overtly symptomatic at birth. The mortality rate in these children is almost 30%; approximately 80% of the
H L, Brown, M P, Abernathy
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Congenital cytomegalovirus infection
Seminars in Perinatology, 2018Each year, thousands of children are born with or develop permanent disabilities such as hearing loss, vision loss, motor and cognitive deficits from congenital CMV infection (cCMV). However, awareness of cCMV and its associated sequelae is very low in pregnant women and healthcare providers.
Karen B, Fowler, Suresh B, Boppana
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Dermatologic Clinics, 2002
Over the past two decades, there has been an escalation in the number of patients undergoing immunosuppressive therapy following solid organ or bone marrow transplantation, as well as a dramatic increase in the incidence of AIDS. As a result, human cytomegalovirus (HCMV)--once considered a neonatal disease--has captured great interest and importance as
Mohamad, Khoshnevis, Stephen K, Tyring
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Over the past two decades, there has been an escalation in the number of patients undergoing immunosuppressive therapy following solid organ or bone marrow transplantation, as well as a dramatic increase in the incidence of AIDS. As a result, human cytomegalovirus (HCMV)--once considered a neonatal disease--has captured great interest and importance as
Mohamad, Khoshnevis, Stephen K, Tyring
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Congenital cytomegalovirus infection
Current Treatment Options in Neurology, 2002Intrauterine infection with cytomegalovirus (CMV), a betaherpesvirus, remains the most frequent congenital virus infection in many regions of the world. Although most CMV-infected newborns lack signs of CMV infection, approximately 10% have signs that can consist of low birth weight, jaundice, hepatosplenomegaly, skin rash, microcephaly, and ...
James F., Bale +2 more
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Congenital cytomegalovirus infections
Seminars in Fetal and Neonatal Medicine, 2007Congenital cytomegalovirus (CMV) infection is one of the most common viral causes of congenital infections in high resource countries and a leading cause of hearing loss as well as an important contributor to neurodevelopmental disabilities in children.
Gunilla, Malm, Mona-Lisa, Engman
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