Results 81 to 90 of about 113,391 (263)

Congenital cytomegalovirus infection

open access: yesAnnals of the New York Academy of Sciences, 2010
Congenital cytomegalovirus (CMV) infection is a serious health problem. The obstacles for limiting this infection are the lack of public awareness on this issue, especially owing to the asymptomatic nature of CMV infections, the inefficacy of therapy, and the unsuccessful vaccine trials to date. It is therefore important to organize the current data to
Syggelou, Angeliki   +4 more
openaire   +3 more sources

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

open access: yesAdvanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng   +7 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

An Evidence Against the Effect of Chronic Cytomegalovirus Infection in Unstable Angina Pectoris [PDF]

open access: yesActa Medica Iranica, 2011
Recent reports have suggested that cytomegalovirus (CMV) infection may contribute to risk of cardiovascular disease. However, relationship between CMV infection and unstable angina (UA) is controversial and studies about this subject in Iran and even ...
Seyed Mohammad Alavi   +2 more
doaj   +2 more sources

Ultrasound indications for maternal STORCH testing in pregnancy

open access: yesSwiss Medical Weekly, 2017
AIMS OF THE STUDY Fetal abnormalities found on ultrasonography lead to a variety of diagnostic procedures, including a panel of serologies to detect possible maternal STORCH infections encompassing syphilis, Toxoplasma gondii, rubella ...
Cora Alexandra Voekt   +4 more
doaj   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

open access: yesAdvanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang   +10 more
wiley   +1 more source

Health Aspects and Pathophysiology of Gestational Infections Causing Disabling Hearing Impairment: Narrative Review

open access: yesIatreia
Introduction: Gestational infectious diseases are significant causes of permanent hearing loss in children under 14 years of age. Although vaccination programs have contributed to the reduction of its prevalence, cases of hearing impairment secondary to ...
Aristizábal-Pérez, Laura Sofía   +4 more
doaj   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

open access: yesAdvanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An   +11 more
wiley   +1 more source

Additional risk factors of ventricular repolarization asynchrony in Q-wave myocardial infarction

open access: yesРоссийский кардиологический журнал, 2007
The study included 101 patients with acute Q-wave infarction. Standard examination was accompanied by assessment of myocardial repolarization dispersion assessment (Day 1 and Day 7) and Chlamydia pneumoniae and Cytomegalovirus infections.
L. E. Lagunina   +2 more
doaj  

Role of TORCH infection in recurrent pregnancy loss [PDF]

open access: yesMinia Journal of Medical Research
BackgroundRecurrent pregnancy loss (RPL) is defined as loss of two or more pregnancies before 24 weeks by both the European Society of Human Reproduction and Embryology and the American Society for Reproductive Medicine.Aim To conduct a comprehensive ...
Hanan Kamel   +3 more
doaj   +1 more source

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