Results 31 to 40 of about 14,151 (225)

Bilateral extensive CMV retinitis in a sick child – Harbinger of severe combined immunodeficiency

Journal of Pediatric Critical Care, 2017
Cytomegalovirus (CMV) retinitis is a marker of severe cellular immunodeficiency. Severe combined immunodeficiency (SCID) must be considered in infants presenting with CMV retinitis in a non-HIV setting.
H S Vinayaka, Tummala Sujith Kumar, G V Basavaraj, Sagar Bhattad   +3 more
doaj   +1 more source

A randomized, controlled trial comparing ganciclovir to ganciclovir plus foscarnet (each at half dose) for preemptive therapy of cytomegalovirus infection in transplant recipients [PDF]

, 2004
Forty-eight patients who provided 2 consecutive blood samples that tested positive for cytomegalovirus DNA by polymerase chain reaction (PCR) were randomized to receive either full-dose ganciclovir ( 5 mg/kg intravenously [iv] twice daily) or half-dose ...
Amooty, G, Brown, VS, Burroughs, AK, Emery, VC, Geretti, AM, Grace, SC, Griffiths, PD, Hainsworth, EG, Mattes, FM, Nebbia, G, Okwuadi, S, Potter, M, Prentice, G, Sabin, C, Sweny, P, Walker, AFH   +15 more
core   +1 more source

High ocular CMV copies and mismatched receipts may predict poor visual prognosis in CMV retinitis patients following allogeneic haematopoietic stem cell transplantation

BMC Ophthalmology, 2017
Background To summarize the clinical characteristics and potential factors affecting the visual outcomes in patients with cytomegalovirus retinitis following allogeneic haematopoietic stem cell transplantation (HSCT).
Yuehong Zhang, Xiangcai Ruan, Weizhong Yang, Ling Li, Zhuanhua Xian, Qiting Feng, Wenjian Mo   +6 more
doaj   +1 more source

AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort [PDF]

, 2017
BackgroundAnecdotal evidence suggests that a high proportion of patients diagnosed with HIV in Guatemala present with AIDS. There remain limited data on the epidemiology of AIDS-defining illnesses (ADIs) in Central America.MethodsWe conducted a ...
Cordon, Andrea Alonzo, Melendez, Johanna, Powderly, William G, Reinhardt, Samuel W, Ross, Ian, Spec, Andrej, Villatoro, Carlos Mejia   +6 more
core   +2 more sources

Bilateral acute necrotizing retinitis due to cytomegalovirus infection in an infant: Challenging case report

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report a case of bilateral acute necrotising retinitis due to cytomegalovirus infection (CMV) in an Asian Indian infant. Observations: An Asian Indian infant born with a birth weight of 1000 g at 26 week of gestation acquired cytomegalovirus ...
Padmamalini Mahendradas, Shivani Sinha, Anand Vinekar, Maralusiddappa Pradeep, Bhujang K. Shetty   +4 more
doaj   +1 more source

Cytomegalovirus Retinitis in infancy [PDF]

Eye, 2004
To describe the presentation of cytomegalovirus retinitis (CMVR) in a series of infants.Immunocompromised infants with either HIV or systemic cytomegalovirus (CMV) were examined for CMVR. Ocular involvement was recorded and monitored by digital imaging.Five infants were detected to have CMVR. All the infants demonstrated changes within the macula.
S M E, Wren, A R, Fielder, D, Bethell, E G H, Lyall, G, Tudor-Williams, K D, Cocker, S M, Mitchell   +6 more
openaire   +2 more sources

The Advent Of Cytomegalovirus Infection In HIV Infected Patients: A review [PDF]

, 2004
Cytomegalovirus is considered as one among the long list of latent infections in humans that although normally controlled by the cellular immune response, gets activated after HIV infection takes its role on infecting the T4 lymphocytes. Clinical disease
Kirubakaran Isaac, Dr Sundar
core   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Cytomegalovirus retinitis in an immunocompetent host after complicated cataract surgery

American Journal of Ophthalmology Case Reports, 2020
Purpose: To report a case of an immunocompetent patient who developed cytomegalovirus (CMV) retinitis after complicated cataract surgery resulting in aphakia.
Drew Scoles, Michael J. Ammar, Robert M. Carroll, Stephen E. Orlin, Victoria Addis, Albert M. Maguire   +5 more
doaj   +1 more source