Results 21 to 30 of about 8,364 (175)

Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis

Case Reports in Medicine, 2018
Cytomegalovirus (CMV) retinitis is one of the rare but debilitating presentations of the CMV infection in children with leukemia. Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse ...
Ali Amanati, Nader Shakibazad, Bahman Pourabbas, Mohammad Hossein Nowroozzadeh, Soheila Zareifar, Omid Reza Zekavat   +5 more
doaj   +1 more source

Cytomegalovirus retinitis following dexamethasone intravitreal implant

American Journal of Ophthalmology Case Reports, 2021
Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient.
Sarah G. Chaudhry, Adrian T. Fung
doaj   +1 more source

Long Term Therapy of Cytomegalovirus Retinitis with Ganciclovir in a Child with Acquired Immunodeficiency Syndrome

Canadian Journal of Infectious Diseases, 1993
Cytomegalovirus retinitis is the most severe ophthalmological complication of patients with acquired immune deficiency syndrome (aids). Ganciclovir must be given continuously to control progression of the disease or relapse typically occurs.
Scott A Halperin, G Robert La Roche
doaj   +1 more source

Bilateral extensive CMV retinitis in a sick child – Harbinger of severe combined immunodeficiency

Journal of Pediatric Critical Care, 2017
Cytomegalovirus (CMV) retinitis is a marker of severe cellular immunodeficiency. Severe combined immunodeficiency (SCID) must be considered in infants presenting with CMV retinitis in a non-HIV setting.
H S Vinayaka, Tummala Sujith Kumar, G V Basavaraj, Sagar Bhattad   +3 more
doaj   +1 more source

High ocular CMV copies and mismatched receipts may predict poor visual prognosis in CMV retinitis patients following allogeneic haematopoietic stem cell transplantation

BMC Ophthalmology, 2017
Background To summarize the clinical characteristics and potential factors affecting the visual outcomes in patients with cytomegalovirus retinitis following allogeneic haematopoietic stem cell transplantation (HSCT).
Yuehong Zhang, Xiangcai Ruan, Weizhong Yang, Ling Li, Zhuanhua Xian, Qiting Feng, Wenjian Mo   +6 more
doaj   +1 more source

CLINICAL MANIFESTATIONS AND CD4 COUNT CHARACTERISTICS OF PATIENTS WITH CYTOMEGALOVIRUS (CMV) RETINITIS

IJRETINA (International Journal of Retina), 2022
Introduction: To describe the clinical manifestations and CD4 count characteristics of patients with cytomegalovirus (CMV) retinitis. Methods: This is a retrospective study of patients diagnosed with CMV retinitis at the Ophthalmology Outpatient ...
Yunneke Renna Xaverina, Ovi Sofia
doaj   +1 more source

Bilateral acute necrotizing retinitis due to cytomegalovirus infection in an infant: Challenging case report

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report a case of bilateral acute necrotising retinitis due to cytomegalovirus infection (CMV) in an Asian Indian infant. Observations: An Asian Indian infant born with a birth weight of 1000 g at 26 week of gestation acquired cytomegalovirus ...
Padmamalini Mahendradas, Shivani Sinha, Anand Vinekar, Maralusiddappa Pradeep, Bhujang K. Shetty   +4 more
doaj   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Vision‐related quality of life following trabeculectomy versus Baerveldt glaucoma implant: Five‐year results from a randomized clinical trial

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the vision‐related quality of life (VRQoL) in glaucoma patients over 5 years after primary Baerveldt glaucoma implant (BGI) or trabeculectomy (TE) using a secondary analysis of a randomized clinical trial. Methods Patients were randomized to undergo TE or receive a BGI.
Ionela Popescu‐Giovanitsas, Jarinne E. Woudstra‐de Jong, Johannes R. Vingerling, Peter W. T. de Waard, Pieter W. M. Bonnemaijer   +4 more
wiley   +1 more source