Results 1 to 10 of about 633,734 (294)
Needle in a Whey-Stack: PhRACS as a Discovery Tool for Unknown Phage-Host Combinations
mBio, 2022 The field of metagenomics has rapidly expanded to become the go-to method for complex microbial community analyses. However, there is currently no straightforward route from metagenomics to traditional culture-based methods of strain isolation ...
Eoghan Casey +17 more
doaj +1 more source
Full Spectrum Flow Cytometry as a Powerful Technology for Cancer Immunotherapy Research
Frontiers in Molecular Biosciences, 2021 The Nobel Prize-deserving concept of blocking inhibitory pathways in T cells, to unleash their anti-tumoral capacity, became one of the pillars of cancer treatment in the last decade and has resulted in durable clinical responses for multiple cancer ...
Diana L. Bonilla +2 more
doaj +1 more source
Computational Analysis of Microbial Flow Cytometry Data
mSystems, 2021 Flow cytometry is an important technology for the study of microbial communities. It grants the ability to rapidly generate phenotypic single-cell data that are both quantitative, multivariate and of high temporal resolution. The complexity and amount of
Peter Rubbens, Ruben Props
doaj +1 more source
Micromachines, 2023 This paper describes, in detail, a method that uses flow cytometry to quantitatively characterise the performance of continuous-flow microfluidic devices designed to separate particles.
Robert Salomon +5 more
doaj +1 more source
Monocyte Phenotypes and Physical Activity in Patients with Carotid Atherosclerosis
Antioxidants, 2022 Atherosclerosis is associated with low-grade inflammation involving circulating monocytes. It has been shown that the levels of intermediate pro-inflammatory monocytes are associated with cardiovascular mortality and risk of ischemic stroke.
Mathilde Mura +10 more
doaj +1 more source
Biotechnology & Biotechnological Equipment, 2021 Hepatitis C is a public health problem worldwide, affecting chronically about 71 million people, or 1% of the world population. The early detection of infection in clinical practice routine and blood donors is still important, being necessary for the ...
Walter Luiz Lima Neves +9 more
doaj +1 more source
High-Dimensional Cytometry Dissects Immunological Fingerprints of Idiopathic Inflammatory Myopathies
Cells, 2022 Chronic inflammation of skeletal muscle is the common feature of idiopathic inflammatory myopathies (IIM). Given the rarity of the disease and potential difficulty of routinely obtaining target tissue, i.e., standardized skeletal muscle, our ...
Christopher Nelke +14 more
doaj +1 more source
eLife, 2021 For an emerging disease like COVID-19, systems immunology tools may quickly identify and quantitatively characterize cells associated with disease progression or clinical response. With repeated sampling, immune monitoring creates a real-time portrait of
Sierra M Barone +7 more
doaj +1 more source
The in vitro micronucleus assay using imaging flow cytometry and deep learning
npj Systems Biology and Applications, 2021 The in vitro micronucleus (MN) assay is a well-established assay for quantification of DNA damage, and is required by regulatory bodies worldwide to screen chemicals for genetic toxicity.
Matthew A. Rodrigues +6 more
doaj +1 more source
Plants, 2020 The cosmopolitan genus Fraxinus comprises about 40 species occupying several habitats in the Northern Hemisphere. With some species hybridizing and sharing genetic variants, questions remain on the species assignment of germplasm within the genus ...
Loredana Abbate +6 more
doaj +1 more source