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Mass Cytometry Imaging for the Study of Human Diseases—Applications and Data Analysis Strategies

open access: yesFrontiers in Immunology, 2019
High parameter imaging is an important tool in the life sciences for both discovery and healthcare applications. Imaging Mass Cytometry (IMC) and Multiplexed Ion Beam Imaging (MIBI) are two relatively recent technologies which enable clinical samples to ...
Heeva Baharlou   +9 more
doaj   +2 more sources

Needle in a Whey-Stack: PhRACS as a Discovery Tool for Unknown Phage-Host Combinations

open access: yesmBio, 2022
The field of metagenomics has rapidly expanded to become the go-to method for complex microbial community analyses. However, there is currently no straightforward route from metagenomics to traditional culture-based methods of strain isolation ...
Eoghan Casey   +17 more
doaj   +1 more source

A compendium of single extracellular vesicle flow cytometry

open access: yesJournal of Extracellular Vesicles, 2023
Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells, which are larger than EVs.
J. Welsh   +23 more
semanticscholar   +1 more source

Flow Cytometry: The Next Revolution

open access: yesCells, 2023
Unmasking the subtleties of the immune system requires both a comprehensive knowledge base and the ability to interrogate that system with intimate sensitivity.
J. Paul Robinson   +4 more
semanticscholar   +1 more source

Monocyte Phenotypes and Physical Activity in Patients with Carotid Atherosclerosis

open access: yesAntioxidants, 2022
Atherosclerosis is associated with low-grade inflammation involving circulating monocytes. It has been shown that the levels of intermediate pro-inflammatory monocytes are associated with cardiovascular mortality and risk of ischemic stroke.
Mathilde Mura   +10 more
doaj   +1 more source

Development of an immunoassay for the detection of human IgG against hepatitis C virus proteins using magnetic beads and flow cytometry

open access: yesBiotechnology & Biotechnological Equipment, 2021
Hepatitis C is a public health problem worldwide, affecting chronically about 71 million people, or 1% of the world population. The early detection of infection in clinical practice routine and blood donors is still important, being necessary for the ...
Walter Luiz Lima Neves   +9 more
doaj   +1 more source

Full Spectrum Flow Cytometry as a Powerful Technology for Cancer Immunotherapy Research

open access: yesFrontiers in Molecular Biosciences, 2021
The Nobel Prize-deserving concept of blocking inhibitory pathways in T cells, to unleash their anti-tumoral capacity, became one of the pillars of cancer treatment in the last decade and has resulted in durable clinical responses for multiple cancer ...
Diana L. Bonilla   +2 more
doaj   +1 more source

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

open access: yesEuropean Journal of Immunology, 2021
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major human and murine immune cell ...
A. Cossarizza   +192 more
semanticscholar   +1 more source

Computational Analysis of Microbial Flow Cytometry Data

open access: yesmSystems, 2021
Flow cytometry is an important technology for the study of microbial communities. It grants the ability to rapidly generate phenotypic single-cell data that are both quantitative, multivariate and of high temporal resolution. The complexity and amount of
Peter Rubbens, Ruben Props
doaj   +1 more source

High-Dimensional Cytometry Dissects Immunological Fingerprints of Idiopathic Inflammatory Myopathies

open access: yesCells, 2022
Chronic inflammation of skeletal muscle is the common feature of idiopathic inflammatory myopathies (IIM). Given the rarity of the disease and potential difficulty of routinely obtaining target tissue, i.e., standardized skeletal muscle, our ...
Christopher Nelke   +14 more
doaj   +1 more source

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