Results 91 to 100 of about 1,338,388 (333)

Prognostic significance of DNA cytometry in cutaneous malignant lymphomas. [PDF]

, 1991
The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome.
Abmayr, Wolfgang, Braun-Falco, Otto, Burg, Günter, Dummer, Reinhard, Eckert, Fritjof, Kaudewitz, Peter, Stolz, Wilhelm, Vogt, Thomas   +7 more
core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Flow cytometry as a tool to identify Mycobacterium tuberculosis interaction with the immune system and drug susceptibility

Memorias do Instituto Oswaldo Cruz, 2000
Flow cytometric analysis is a useful and widely employed tool to identify immunological alterations caused by different microorganisms, including Mycobacterium tuberculosis. However, this tool can be used for several others analysis. We will discuss some
Maria da Gloria Bonecini-Almeida
doaj   +1 more source

Differential leukocyte count method for bovine low somatic cell count milk [PDF]

, 2003
Whereas many differential leukocyte count methods for high somatic cell count (SCC) milk from mastitic cows are available, only a few have been developed for low SCC milk.
Burvenich, Christian, Dosogne, Hilde, MASSART-LEEN, AM, MEHRZAD, J, Vangroenweghe, Frédéric   +4 more
core   +2 more sources

CytoNorm: A Normalization Algorithm for Cytometry Data

Cytometry Part A, 2019
High‐dimensional flow cytometry has matured to a level that enables deep phenotyping of cellular systems at a clinical scale. The resulting high‐content data sets allow characterizing the human immune system at unprecedented single cell resolution ...
S. van Gassen, Brice L Gaudilliere, M. Angst, Y. Saeys, N. Aghaeepour   +4 more
semanticscholar   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Comparative Analysis of Nucleus Segmentation Techniques for Enhanced DNA Quantification in Propidium Iodide-Stained Samples

Applied Sciences
Digitization in pathology and cytology labs is now widespread, a significant shift from a decade ago when few doctors used image processing tools. Despite unchanged scanning times due to excitation in fluorescent imaging, advancements in computing power ...
Viktor Zoltán Jónás, Róbert Paulik, Béla Molnár, Miklós Kozlovszky   +3 more
doaj   +1 more source

Fluctuation of Information Entropy Measures in Cell Image

Entropy, 2017
A simple, label-free cytometry technique is introduced. It is based on the analysis of the fluctuation of image Gray Level Information Entropy (GLIE) which is shown to reflect intracellular biophysical properties like generalized entropy.
Ishay Wohl, Naomi Zurgil, Yaron Hakuk, Maria Sobolev, Mordechai Deutsch   +4 more
doaj   +1 more source

Human Amniocytes Are Receptive to Chemically Induced Reprogramming to Pluripotency [PDF]

, 2017
Restoring pluripotency using chemical compounds alone would be a major step forward in developing clinical-grade pluripotent stem cells, but this has not yet been reported in human cells.
Adjaye, J, Campanella, M, De Coppi, P, Eaton, S, Faccenda, D, Guillot, P V, Hau, K-L, Hawkins, K E, Martin-Trujillo, A, Monk, D, Moschidou, D, Ranzoni, A M, Sanchez-Freire, V, Thrasher, A J, Tommasini, F, Wruck, W   +15 more
core   +3 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source