Results 121 to 130 of about 633,734 (294)
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock +8 more
wiley +1 more source
Interinstitutional variability in DNA flow cytometric analysis of tumors. The National Cancer Institute's flow cytometry network experience [PDF]
, 1988 John S. Coon +8 more
openalex +1 more source
Advanced Biology, EarlyView.The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo +5 more
wiley +1 more source
DNA image cytometry on machine‐selected breast cancer cells and a comparison between flow cytometry and scanning cytophotometry [PDF]
, 1985 Cornelis J. Cornelisse +1 more
openalex +1 more source
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
Advanced Biology, EarlyView.RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang +13 more
wiley +1 more source
Rapid detection of Legionella pneumophila by flow cytometry [PDF]
, 1982 Marylou Ingram +4 more
openalex +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Detection of Escherichia coli in blood using flow cytometry [PDF]
, 1985 J D Mansour +3 more
openalex +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Advanced Biology, EarlyView.Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav +5 more
wiley +1 more source