Results 201 to 210 of about 937,182 (344)

Flow Cytometry: An Overview

Current Protocols in Immunology, 2018
K. McKinnon
semanticscholar   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Editorial: The use of image and imaging flow cytometry as a tool to study host-pathogen interactions

Frontiers in Cellular and Infection Microbiology, 2022
Dominic C. Jenner, Aja M. Rieger, Ziv Porat   +2 more
doaj   +1 more source

Baicalein inhibits mycobacterium tuberculosis-induced macrophage M1 polarization depending on the regulation of YY1/RAB10/TLR4 pathway. [PDF]

J Inflamm (Lond)
Zhou Q, Chen S, Shu L, Wang Q, Yuan T, Ou Y, Qing L, He X.   +7 more
europepmc   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

A multistep platform identifies spleen-tropic lipid nanoparticles for in vivo T cell-targeted delivery of gene-editing proteins. [PDF]

Sci Adv
Lu X, Zhu Y, Wei C, Cheng L, Goodier KD, Kong J, Gao X, Yu D, Liu X, Long Y, Lin J, Ma J, Su Y, Mao HQ.   +13 more
europepmc   +1 more source

Quantitative description of classic and variant small cell lung cancer cell lines by nuclear image cytometry [PDF]

, 1988
J. L. V. Broers, M. M. M. Pahlplatz, Michael W. Katzko, Peter S. Oud, Frans C. S. Ramaekers, D N Carney, G. Peter Vooijs   +6 more
openalex   +1 more source

A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry.

Cell Metabolism, 2019
Nicolas Damond, S. Engler, V. Zanotelli, D. Schapiro, C. Wasserfall, I. Kusmartseva, H. Nick, F. Thorel, P. Herrera, M. Atkinson, B. Bodenmiller   +10 more
semanticscholar   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

The role and mechanism of transcription factor KLF4 in regulating mitochondrial damage and apoptosis by activating chondrocyte autophagy in osteoarthritis. [PDF]

Sci Rep
Feng W, Wang H, Zhang G, Gao W, Li H, Liu H, Sun Y.   +6 more
europepmc   +1 more source