Results 201 to 210 of about 615,339 (319)

Short‐Chain Fatty Acids Modulate Anti‐ROR1 CAR T‐Cell Function and Exhaustion in an Intestinal Adenocarcinoma‐on‐Chip Model

Advanced Healthcare Materials, EarlyView.
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner, Adrian Feile, Miriam Alb, Michael Hudecek, Philip Hewitt, Alexander S. Mosig   +5 more
wiley   +1 more source

Editorial: The use of image and imaging flow cytometry as a tool to study host-pathogen interactions

Frontiers in Cellular and Infection Microbiology, 2022
Dominic C. Jenner, Aja M. Rieger, Ziv Porat   +2 more
doaj   +1 more source

Polysialic acid is upregulated on activated immune cells and negatively regulates anticancer immune activity. [PDF]

Front Oncol
Drummond-Guy O, Daly J, Wu A, Stewart N, Milne K, Duff C, Nelson BH, Williams KC, Wisnovsky S.   +8 more
europepmc   +1 more source

Modular electronics for flow cytometry and sorting: The LACEL system [PDF]

, 1981
Randy Hiebert, James H. Jett, G.C. Salzman   +2 more
openalex   +1 more source

Matrix Viscoelasticity Orchestrates Osteogenesis via Mechanotransduction Mediated Metabolic Switch in Macrophages

Advanced Healthcare Materials, EarlyView.
Fast‐relaxation viscoelastic hydrogel triggers a metabolic shift in macrophages, favoring oxidative phosphorylation (OXPHOS) over glycolysis via vasodilator‐stimulated phosphoprotein (VASP) / hypoxia‐inducible factor 1 alpha (HIF1α) signaling meditated mechanotransdution, thereby enhancing their capacity to recruit mesenchymal stem cells (MSCs) and ...
Dihao Tao, Hanzhe Wang, Shiping Chang, Jiayu Cheng, Ningning Da, Li Zhang, Jianhua Yang, Wenzhe Wang, Feng Xu, Bei Li   +9 more
wiley   +1 more source

Rapid detection of Legionella pneumophila by flow cytometry [PDF]

, 1982
Marylou Ingram, Timothy J. Cleary, Brandon J. Price, Relf L. Price, Albert Castro   +4 more
openalex   +1 more source

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis

Advanced Healthcare Materials, EarlyView.
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu, Joel M. Yong, Robyn Yeh, Florence Bartlett, John M. Whitelock, Megan S. Lord   +5 more
wiley   +1 more source

NKG2D/CD28 chimeric receptor boosts cytotoxicity and durability of CAR-T cells for solid and hematological tumors. [PDF]

Exp Hematol Oncol
Teng X, Li S, Zhang C, Ding H, Tian Z, Zhu Y, Liu T, Zhang G, Sun K, Xie H, Tu J, Lu Z.   +11 more
europepmc   +1 more source

Cigarette smoking and human sperm quality assessed by laser-Doppler spectroscopy and DNA flow cytometry [PDF]

, 1989
Nan Birgitte Oldereid, Hallgeir Rui, O. P. F. Clausen, K. Purvis   +3 more
openalex   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

Advanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth, Zachary S.C.S. Froom, Natasha D. Osborne, Christian N. Rempe, Brenden Wheeler, Kyle Medd, Neal I. Callaghan, Huikang Qian, Abhinav P. Acharya, Carlie Charron, Locke Davenport Huyer   +10 more
wiley   +1 more source