Results 231 to 240 of about 1,044,820 (327)

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Flow cytometry for screening and prioritisation of urine samples: a retrospective comparison with culture. [PDF]

BMC Infect Dis
Sender V, White JK, Bolinder L, Amilon K, Hägg M, Bhattarai KH, Björkström NK, Saeedi B.   +7 more
europepmc   +1 more source

Comparative analysis of lymphocyte phenotypes between carriers of human immunodeficiency virus(HIV) and adult patients with primary immunodeficiency using two-color immunofluorescence flow cytometry.

, 1988
Tatsuharu Ohno, T Kanoh, Takayo Suzuki, Tohru Masuda, Kagemasa Kuribayashi, Shinichi Araya, HISAJI ARAI, Haruto Uchino   +7 more
openalex   +2 more sources

SPURIOUS LYMPHOCYTE PHENOTYPES BY FLOW CYTOMETRY FROM MONONUCLEAR CELLS PREPARED BY FICOLL-HYPAQUE [PDF]

, 1987
Herbert B. Slade, Jay H. Greenwood, Jerry L. Hudson, Robert H. Beekman, J. Philip McCoy, Standley A Schwartz   +5 more
openalex   +1 more source

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

Advanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila, Anh Ha, Morgan R. Chandler, Nathalia Leal Santos, Taejin Kim, Hannah S. Newton, Marina A. Dobrovolskaia, Kirill A. Afonin   +7 more
wiley   +1 more source

CD155 as a therapeutic target in alveolar echinococcosis: insights from an <i>Echinococcus multilocularis</i> infection mouse model. [PDF]

Front Microbiol
Zhang X, Li L, Sun T, Yang N, Liu H, Chu J, Xue J, Lü G, Aji T, Bi X, Lin R.   +10 more
europepmc   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Therapeutic effects of hypoimmunogenic universal human iPSC-derived endothelial cells in a humanized mouse model of peripheral artery disease. [PDF]

Stem Cell Res Ther
Choi J, Kim NG, Kong D, Kim MJ, Kang BC, Kwon D, Kim DH, Kang KS.   +7 more
europepmc   +1 more source

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source