Results 241 to 250 of about 615,339 (319)

USP15-modified ADMSCs-Exo alleviates chondrocyte damage and effectively relieved osteoarthritis by inducing M2 polarization of macrophages through deubiquitinating FOXC1. [PDF]

J Orthop Surg Res
Liang Q, Ding Q, Zhao L, Tan J, Niu W.
europepmc   +1 more source

Extracellular Vesicle Crosslinkers Constructing Hydrogels with Stress‐Relaxation and Bioactive Protein Modification

Advanced Materials Interfaces, EarlyView.
Extracellular vesicles (EVs) are functionalized and used as crosslinkers to construct hydrogels, compatible with common crosslinking chemistries in biomaterial scaffolds. EV crosslinkers provided stress relaxation properties, promoting cell growth. They also enabled efficient protein delivery while maintaining biological activity, as VEGF‐loaded EV ...
Lufeng Shi, Yanzhen Jing, Haowen Lu, Fanxuan Zhao, Mengying An, Shuiling Jin, Chang Gao, Yongdong Dai, Yinxin Zhu, Shuxu Yang, Songying Zhang, Xuesong Ye, Xiujun Cai, Yifan Wang, Shangjing Xin   +14 more
wiley   +1 more source

ESCRT III Regulates Lysosomal Perinuclear Clustering by Inhibiting Kinesin 1 Leading to Agnps Cytotoxicity in Human Cells

Advanced Materials Interfaces, EarlyView.
AgNPs cause significant damage upon entering the lysosomes of human fibroblasts, resulting in lysosomal transport disorders and the occurrence of perinuclear clustering (LPC) of lysosomes by promoting apoptosis that is accompanied by a reduction in the expression levels of ESCRT III and Kinesin 1 proteins.
Tiantian Liu, Aiguo Xie, Chao Xing, RuiZhe He, Wei Ni, Yinbo Peng, Peng Xu, Yong Fang   +7 more
wiley   +1 more source

Assay of cardiopulmonary bypass system for porcine alveolar macrophages removing GFP-<i>E. coli</i> from erythrocyte surfaces. [PDF]

PeerJ
Liu Y, Wang N, Ru Q, Fan K, Sun N, Sun P, Li H, Yin W.   +7 more
europepmc   +1 more source

Computationally Guided Liquid Crystal‐Based Competitive Binding Sensing Platform for Optical Detection of Spike Protein

Advanced Materials Technologies, EarlyView.
A competitive‐binding paradigm for detection of viruses with the detection of the receptor binding domain of the spike protein as an illustrative example is introduced. Importantly, this approach does not rely on antibodies and therefore is of significance for detecting novel and emerging pathogens. Abstract A liquid crystal (LC)‐based sensing platform
Homa Ghaiedi, Shubham Pandey, Sophia Ezendu, Tibor Szilvási, Karthik Nayani   +4 more
wiley   +1 more source

Impact of tumor localization on antitumor immunity with conditionally activated CTLA-4 blockade. [PDF]

J Immunother Cancer
Arias-Badia M, Pai CS, Lwin YM, Chen P, Srinath A, Tanaka M, Musser E, Goodearl A, Gorman JV, Ritacco W, Fong L.   +10 more
europepmc   +1 more source

The Role of Silicon Technology in Organ‐On‐Chip: Current Status and Future Perspective

Advanced Materials Technologies, EarlyView.
This review explores the potential of silicon micro‐nanofabrication technologies in advancing organ‐on‐chip systems. The integration of actuation and sensing modalities, highlight emerging technologies is discussed for combining silicon‐based and polymer‐based components, and emphasize the need for robust, high‐throughput, and customizable organ‐on ...
Frøydis Sved Skottvoll, Enrique Escobedo‐Cousin, Michal Marek Mielnik   +2 more
wiley   +1 more source

A novel anti-mouse CXCR1 monoclonal antibody, Cx₁Mab-8, demonstrates nanomolar affinity in flow cytometry. [PDF]

Biochem Biophys Rep
Li G, Suzuki H, Tanaka T, Satofuka H, Kaneko MK, Kato Y.   +5 more
europepmc   +1 more source

Evaporation‐Enhanced Redox Cycling for Rapid Detection of Attomolar SARS‐CoV‐2 Virions Using Nanolithography‐Free Electrochemical Devices

Advanced Materials Technologies, EarlyView.
This study presents microfabricated electrochemical sensors for detecting ultralow viral particles counts through evaporation‐enhanced redox cycling (E2RC). To achieve sub‐micrometer gap in interdigitated microelectrodes, a scalable, nanolithography‐free fabrication method is developed.
Pouya Soltan Khamsi, Vinay Kammarchedu, Aida Ebrahimi   +2 more
wiley   +1 more source