Results 241 to 250 of about 1,044,820 (327)

<i>Ex vivo-</i>generated lymphoid progenitors encompass both T cell and innate lymphoid cell fates. [PDF]

Front Immunol
Gaudeaux P, Paillet J, Abou Alezz M, Moirangthem RD, Cascione S, Martin Corredera M, Dolens AC, De Mulder K, Velghe I, Vandekerckhove B, Lavaert M, Robil N, Corneau A, Sadek H, Rault P, Joshi A, de la Grange P, Staal FJT, Taghon T, Negre O, Ditadi A, André I, Soheili TS.   +22 more
europepmc   +1 more source

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel, Henning De May, Lauren Anderson, Lorél Y. Medina, Ellie Kennedy, Erica Flores, John O'Rourke, Marian Olewine, Irina Lagutina, Lillian Fitzpatrick, Fred Shultz, Donna F. Kusewitt, Eric Bartee, Sarah Adams, Achraf Noureddine, Rita E. Serda   +15 more
wiley   +1 more source

Correction to "CD312 Promotes Pediatric Acute Lymphoblastic Leukemia Through GNA15 Mediated Non-Classical GPCR Signaling Pathway". [PDF]

J Cell Mol Med
europepmc   +1 more source

Automated descriptive cell type naming in flow and mass cytometry with CytoPheno. [PDF]

Sci Rep
Tursi AR, Lages CS, Quayle K, Koenig ZT, Loni R, Eswar S, Cobeña-Reyes J, Thornton S, Tilburgs T, Andorf S.   +9 more
europepmc   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

Langerhans cells drive Tfh and B cell responses independent of canonical cytokine signals. [PDF]

Front Immunol
Bouteau A, Qin Z, Zurawski S, Zurawski G, Igyártó BZ.   +4 more
europepmc   +1 more source

Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting

Advanced Healthcare Materials, EarlyView.
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari, Mahdieh Shokrollahi Barough, Amir Seyfoori, Mahmood Razzaghi, Joel Alexander Ninan, Aidan B. P. Murray, Mahmoud Salkhordeh, Yuan Tan, Shirley H. J. Mei, Mohsen Akbari   +9 more
wiley   +1 more source

Author Correction: Fibroblast derived C3 promotes the progression of experimental periodontitis through macrophage M1 polarization and osteoclast differentiation. [PDF]

Int J Oral Sci
Ren F, Zheng S, Luo H, Yu X, Li X, Song S, Bu W, Sun H.   +7 more
europepmc   +1 more source

Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections

Advanced Healthcare Materials, EarlyView.
Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic, Evangelos Natsaridis, Timon Flathmann, Daiane P. C. Quadros, Nubia Gogniat, Oya Tagit   +5 more
wiley   +1 more source

Lung metastasis and recurrence is mitigated by CAR macrophages, in-situ-generated from mRNA delivered by small extracellular vesicles. [PDF]

Nat Commun
Xiao Y, Zhu T, Chen Z, Huang X.
europepmc   +1 more source