Results 51 to 60 of about 615,339 (319)

Long-term culture-initiating cells (LTC-IC) produced from CD34+ cord blood cells with limiting dilution method

open access: yesTurkish Journal of Hematology, 2010
OBJECTIVE: Even though much progress has been made in defining primitive hematologic cell phenotypes by using flow cytometry and clonogenic methods, the direct method for study of marrow repopulating cells still remains to be elusive.
Gülderen Yanıkkaya Demirel   +3 more
doaj   +3 more sources

ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data

open access: yeseLife, 2021
High-dimensional cytometry is an innovative tool for immune monitoring in health and disease, and it has provided novel insight into the underlying biology as well as biomarkers for a variety of diseases.
James W Opzoomer   +17 more
doaj   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

An Antimicrobial Peptide Induces FIG1-Dependent Cell Death During Cell Cycle Arrest in Yeast

open access: yesFrontiers in Microbiology, 2018
Although most antibiotics act on cells that are actively dividing and non-dividing cells such as in microbe sporulation or cancer stem cells represent a new paradigm for the control of disease.
Vladimir J. Arellano   +9 more
doaj   +1 more source

Improving oligo-conjugated antibody signal in multimodal single-cell analysis

open access: yeseLife, 2021
Simultaneous measurement of surface proteins and gene expression within single cells using oligo-conjugated antibodies offers high-resolution snapshots of complex cell populations.
Terkild B Buus   +9 more
doaj   +1 more source

CytOpT: Optimal Transport with Domain Adaptation for Interpreting Flow Cytometry data [PDF]

open access: yesarXiv, 2020
The automated analysis of flow cytometry measurements is an active research field. We introduce a new algorithm, referred to as CytOpT, using regularized optimal transport to directly estimate the different cell population proportions from a biological sample characterized with flow cytometry measurements.
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Dimensionnement et extrapolation des bioréacteurs sur base de paramètres physiologiques : cas de la production de lipase par Yarrowia lipolytica [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2011
Bioreactor scale-up and design on the basis of physiologically relevant parameters: application to the production of lipase by Yarrowia lipolytica.
Kar, T.   +3 more
doaj  

Effective viscosity of methyl cellulose solutions in phosphate buffered saline in real-time deformability cytometry [PDF]

open access: yesarXiv, 2023
Here, we derive the equations to calculate the effective viscosity of solutions of methyl cellulose (MC) dissolved in phosphate buffered saline (PBS) in real-time deformability cytometry (RT-DC) experiments. The calculations are based on the rheometer measurements described by B\"uy\"ukurganci et al. (2022).
arxiv  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

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