Results 71 to 80 of about 1,097,210 (332)

Spectral Flow Cytometry [PDF]

open access: yesCurrent Protocols in Cytometry, 2013
AbstractInterest in measuring the complete fluorescence spectra of individual cells in flow can be traced to the earliest days of flow cytometry. Recent advances in detectors, optics, and computation have made it possible to make full spectral measurements in the sub‐millisecond time frame in which flow cytometry measurements typically occur.
John P, Nolan, Danilo, Condello
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Comparative Analysis of Nucleus Segmentation Techniques for Enhanced DNA Quantification in Propidium Iodide-Stained Samples

open access: yesApplied Sciences
Digitization in pathology and cytology labs is now widespread, a significant shift from a decade ago when few doctors used image processing tools. Despite unchanged scanning times due to excitation in fluorescent imaging, advancements in computing power ...
Viktor Zoltán Jónás   +3 more
doaj   +1 more source

Flow cytometry as a tool to identify Mycobacterium tuberculosis interaction with the immune system and drug susceptibility

open access: yesMemorias do Instituto Oswaldo Cruz, 2000
Flow cytometric analysis is a useful and widely employed tool to identify immunological alterations caused by different microorganisms, including Mycobacterium tuberculosis. However, this tool can be used for several others analysis. We will discuss some
Maria da Gloria Bonecini-Almeida
doaj   +1 more source

CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. [PDF]

open access: yes, 2019
Ovarian cancer and triple-negative breast cancer are among the most lethal diseases affecting women, with few targeted therapies and high rates of metastasis. Cancer cells are capable of evading clearance by macrophages through the overexpression of anti-
Barkal, Amira A   +10 more
core  

Differential leukocyte count method for bovine low somatic cell count milk [PDF]

open access: yes, 2003
Whereas many differential leukocyte count methods for high somatic cell count (SCC) milk from mastitic cows are available, only a few have been developed for low SCC milk.
Burvenich, Christian   +4 more
core   +2 more sources

Magnetic Twisting Cytometry

open access: yesCold Spring Harbor Protocols, 2011
INTRODUCTIONThis protocol provides the general steps for magnetic twisting cytometry (MTC). MTC is an active microrheology method well-suited to measuring the mechanical properties of the individual adherent cells. Specialized equipment is required for producing the magnetic fields used in this technique.
Kasza, K. E.   +7 more
openaire   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Lab-On-A-Chip Device for Yeast Cell Characterization in Low-Conductivity Media Combining Cytometry and Bio-Impedance

open access: yesSensors, 2019
This paper proposes a simple approach to optimize the operating frequency band of a lab-on-a-chip based on bio-impedance cytometry for a single cell. It mainly concerns applications in low-conductivity media. Bio-impedance allows for the characterization
Julien Claudel   +3 more
doaj   +1 more source

The ciliary GTPase Arl13b regulates cell migration and cell cycle progression [PDF]

open access: yes, 2016
Acknowledgments We acknowledge Prof. Tamara Caspary from Emory University for kindly providing the cell lines, Linda Duncan from the University of Aberdeen Ian Fraser Cytometry Center for help with flow cytometry.
Clancy, Hannah   +6 more
core   +2 more sources

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