Results 41 to 50 of about 1,409 (128)

Cytomorphological evaluation of tuberculous lymphadenitis and its correlation with Ziehl–Neelsen staining and cartridge-based nucleic acid amplification test

open access: yesMGM Journal of Medical Sciences
Background: Tuberculous lymphadenitis accounts for a major proportion of extrapulmonary tuberculosis (TB) cases worldwide. Fine-needle aspiration cytology (FNAC) reveals characteristic cytomorphological patterns that are highly suggestive of TB.
Rajasree Chakrabarty   +5 more
doaj   +1 more source

Molecular profiling of pediatric medulloblastoma in Kazakhstan: Genomic alterations, subgroup distribution, and survival

open access: yesBrain Pathology, EarlyView.
A practical formalin‐fixed, paraffin‐embedded (FFPE)‐based molecular workflow integrating pathology, immunohistochemistry, and genomic profiling provides clinically meaningful subgroup classification of pediatric medulloblastoma and expands molecular evidence from an underrepresented Central Asian population. Abstract Medulloblastoma is the most common
Aidos Bolatov   +9 more
wiley   +1 more source

PDGFD‐Rearranged Dermatofibrosarcoma Protuberans With S100 and Pan‐TRK Expression

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatofibrosarcoma protuberans (DFSP) is a fibroblastic malignancy characterized in most cases by COL1A1::PDGFB fusion. Rare cases exhibit alternative rearrangements involving PDGFD. Here, we describe a female patient in her third decade of life who presented with a spindle cell proliferation on the shoulder.
Venezia Podesta   +4 more
wiley   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

open access: yesCytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu   +3 more
wiley   +1 more source

Diagnostic Utility of the Milan System for Reporting Salivary Gland Cytopathology With Cytohistological Correlation

open access: yesCytopathology, EarlyView.
This retrospective study reviews 111 salivary gland fine‐needle aspiration cytology (FNAC) cases collected over an 11‐year period and reclassifies them according to the Milan System for Reporting Salivary Gland Cytopathology. Cytology‐histopathology correlation was performed for excision specimens, confirming the system's accuracy in distinguishing non‐
Shifa F. Khan   +4 more
wiley   +1 more source

Implementation of Bethesda system in thyroid aspirate: A cyto-histopathological correlation study

open access: yesJournal of Pathology of Nepal, 2016
Background: Thyroid lump is a common clinical problem in Nepal. The risk of malignancy has to be judged prior to surgery for which fine needle aspiration cytology is widely used.
PK Choudhary   +3 more
doaj   +1 more source

Progressive Pulmonary Alveolar Proteinosis Diagnosis Masking Pneumonic Lung Carcinoma: Anchoring Bias in Critical Care

open access: yesCytopathology, EarlyView.
A presumed case of pulmonary alveolar proteinosis with clinical deterioration was ultimately identified at autopsy as pneumonic‐type pleomorphic carcinoma. This case highlights the diagnostic overlap between diffuse lung diseases and the risk of anchoring bias in critically ill patients.
Dakota Wheeler   +3 more
wiley   +1 more source

Hippo pathway disruption and YAP1 activation in anogenital papillary squamous intraepithelial lesion

open access: yesHistopathology, EarlyView.
Disruption of the Hippo Pathway with YAP1 activation is a consistent finding in papillary squamous intraepithelial lesions and may underlie their altered epithelial maturation and HPV E6/E7 expression patterns, providing new insight into the pathogenesis of this distinct low‐risk HPV‐associated lesion.
Gloria Zhang   +4 more
wiley   +1 more source

Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK‐positive anaplastic large‐cell lymphoma

open access: yesHistopathology, EarlyView.
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin   +6 more
wiley   +1 more source

Cytological spectrum of suppurative cutaneous and subcutaneous nodules: a one-year retrospective observational study at a tertiary care hospital.

open access: yesStudent's Journal of Health Research Africa
Background: Suppurative cutaneous and subcutaneous nodules frequently resemble a wide range of inflammatory and neoplastic lesions, making early diagnosis essential.
Dr. Lakshmi Saraswathi Boni   +3 more
doaj   +1 more source

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