Results 51 to 60 of about 5,295 (175)

Antiviral Activity of the Sesquiterpene Lactones from against Influenza a Virus

Natural Product Communications, 2018
During the course of searching for antiviral agents from Chinese medicinal herbs, we found that the supercritical fluid extract (SFE) of Centipeda minima possessed good in vitro antiviral activity against influenza virus A/Puerto Rico/8/34 H1N1 (PR8 ...
Xiaoli Zhang, Jun He, Weihuan Huang, Huibin Huang, Zeming Zhang, Jiajian Wang, Li Yang, Guocai Wang, Yifei Wang, Yaolan Li   +9 more
doaj   +1 more source

Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity

Molecular Microbiology, Volume 125, Issue 2, Page 145-158, February 2026.
Mycoplasma pneumoniae pathogenesis relies on its CARDS toxin, which initiates cell binding and subsequent uptake by exploiting sphingomyelin, a key phospholipid found in the host plasma membrane. Maximal cellular entry and full cytotoxic effects are achieved through a synergistic mechanism that involves interaction with the protein coreceptor annexin ...
Alejandra M. Kirkpatrick, Thirumalai R. Kannan   +1 more
wiley   +1 more source

[Use of cross-absorbed sera in neutralization tests with viral titration by the cytopathogenic effect].

Voprosy virusologii, 1975
A new method for intratypic antigenic differentiation of poliovirus strains has been developed. The method is based on the use of cross-absorbed sera in neutralization tests where virus is titrated by the cytopathic effect. Qualitative differences between the antigenic structure of vaccine and "wild" strains as well as between some "wild" strains of ...
Iu V, Pervikov, M P, Chumakov, M K, Voroshilova, S G, Rubin   +3 more
openaire   +1 more source

Influenza Surveillance in the Central African Republic From 2015 to 2018 to Inform Vaccination and Treatment Strategies

Influenza and Other Respiratory Viruses, Volume 20, Issue 1, January 2026.
ABSTRACT Background Surveillance of influenza infections and virus characterisation are essential to guide prevention strategies. In the Central African Republic (CAR), data on influenza viruses are patchy and poorly documented. Objective To study the clinical, seasonal, genetic and phenotypic characteristics of influenza viruses circulating in the CAR
Giscard Francis Komoyo, Chantal J. Snoeck, Rod S. Daniels, Marie R. Belizaire, Judith M. Hübschen, Claude P. Muller, Pierre Somse, Yap Boum II, Emmanuel Nakoune, John W. McCauley   +9 more
wiley   +1 more source

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

In vitro and in vivo expression of foreign genes by transmissible gastroenteritis coronavirus-derived minigenomes

, 2002
A helper-dependent expression system based on transmissible gastroenteritis coronavirus (TGEV) has been developed using a minigenome of 3·9 kb (M39).
Enjuanes, L., Plana-Duran, J., Reimann, I., Moormann, R.J.M., Sola, I., Plana Duran, J., Alonso, S., Izeta, A., Teifke, J.P., Teifke, Jens Peter, Reimann, Ilona, Balasch, M.   +11 more
core   +1 more source

Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication

Journal of Traditional and Complementary Medicine, 2011
Development of anti-severe acute respiratory syndrome associated coronavirus (SARS-CoV) agents is pivotal to prevent the reemergence of the life-threatening disease, SARS.
Chih-Chun Wen, Lie-Fen Shyur, Jia-Tsrong Jan, Po-Huang Liang, Chih-Jung Kuo, Palanisamy Arulselvan, Jin-Bin Wu, Sheng-Chu Kuo, Ning-Sun Yang   +8 more
doaj   +1 more source

Innovation in Green Extraction of Essential Oils From Medicinal Aromatic Plants and Their Nano‐Formulation With Potential Anti‐Respiratory Viruses Activities

eFood, Volume 6, Issue 6, December 2025.
Essential oils (EOs) from peppermint, thyme, eucalyptus, and lemongrass were extracted and characterized by GC‐MS, then combined and nano‐formulated. All extracts showed antiviral activity, with the nano‐mixture exhibiting the strongest effect against influenza A and SARS‐CoV‐2.
Sobhy Mohamed Mohsen, Mahmoud Mohamed Bahgat, Azza A. Amin, Amr M. Helal, Dina Nadeem Abd‐Elshafy, Sayed Saad Smuda, Mohammad Ali Hesarinejad, Tarek Gamal Abedelmaksoud   +7 more
wiley   +1 more source

The Biological Characteristics and Mouse Model of Lassa Virus From the First Imported Case in China

MedComm, Volume 6, Issue 8, August 2025.
This is the first case of Lassa fever being introduced to China. A strain of the Lineage IV LASV was successfully isolated, and genomic and mutation analysis were conducted. Infection models were constructed using BALB/c, C57BL/6, and AG129 mice, which were successfully established.
Yanan Zhou, Junbin Wang, Ranran Cao, Yun Yang, Yuliang Feng, Cong Tang, Hao Yang, Qing Huang, Wenhai Yu, Haixuan Wang, Jiandong Shi, Kaiyun Ding, Longhai Yuan, Qing Dai, Xingping Zhao, Haiyan Li, Mengli Yang, Fangyu Luo, Fanli Zhu, Yong Zhang, Daoju Wu, Xiaorong Yang, Shuaiyao Lu, Qiangming Sun, Li Zhang, Youchun Wang   +25 more
wiley   +1 more source

Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review

Global Challenges, Volume 9, Issue 5, May 2025.
Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze, Gianluigi Franci, Federica Dell'Annunziata, Nicoletta Capuano, Marica Colella, Flora Salzano, Massimiliano Galdiero, Aliosha Bakuridze, Veronica Folliero   +8 more
wiley   +1 more source