Results 31 to 40 of about 5,331 (138)

Hypertrophic genital herpes in an HIV-infected female patient: Imiquimod as an alternative treatment

International Journal of Infectious Diseases, 2020
Herpes Simplex Virus (HSV) is the leading cause of genital ulcers worldwide. In Human Immunodeficiency Virus (HIV) co-infected individuals, rare hypertrophic pseudo-tumoral forms have been described as simulating squamous cell carcinoma or other viral ...
Helena Lucia Barroso dos Reis, Neide Aparecida Tosato Boldrini, Luisa Cardoso da Silva Campos, Letícia Goulart Campos, Franco Luis Salume Costa, João Victor Jacomele Caldas, Susana Lamara Pedras Almeida, Angelica Espinosa Miranda   +7 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

SARS-CoV-2 infection diagnosed only by cell culture isolation before the local outbreak in an Italian seven-week-old suckling baby

International Journal of Infectious Diseases, 2020
SARS-CoV-2 emerged in China in December 2019 and has now been declared a pandemic by the World Health Organization. This paper described the case of a 7-week-old suckling baby from Italy who was SARS-CoV-2-positive only by the cell culture method, with ...
Adriana Calderaro, Maria Cristina Arcangeletti, Flora De Conto, Mirko Buttrini, Paolo Montagna, Sara Montecchini, Francesca Ferraglia, Federica Pinardi, Carlo Chezzi   +8 more
doaj   +1 more source

B‐Cell Depletion Relative to Tumor Necrosis Factor Inhibition Extends the Duration of Viral Shedding in COVID‐19 Among Autoimmune Disease Patients: A Matched Prospective Cohort Study

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective To investigate SARS‐CoV‐2 viral shedding duration in autoimmune patients using B cell depleting (BCD) therapy or tumor necrosis factor inhibitors (TNFi) and immunocompetent comparators. Methods We conducted a matched cohort analysis among participants in POSITIVES, a prospective study enrolling outpatients with acute COVID‐19 within five days
Liya Sisay Getachew, Xiaosong Wang, Naomi J. Patel, Zachary S. Wallace, Lauren A. O'Keeffe, Madison Negron, Jiaqi Wang, Grace Qian, Alene A. Saavedra, Kevin T. Mueller, Natalie Davis, Yijia Li, Brooke M. Leeman, Manish C. Choudhary, Sebastien Haneuse, Luke Benz, Julie Boucau, Gregory E. Edelstein, Owen T. Glover, Yumeko Kawano, Rinki Deo, Zahra Reynolds, Karry Su, Chase B. Mandell, Zoie Smith‐Sparks, Eliza Passell, Mamadou Oury Barry, Dessie Tien, Sarah P. Hammond, Gaurav D. Gaiha, Jacob E. Lemieux, Amy K. Barczak, Jonathan Z. Li, Mark J. Siedner, Jeffrey A. Sparks   +34 more
wiley   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, Volume 13, Issue 39, 13 July 2026.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

2‐Phenylquinolines Exhibit Anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 Activity Through the Nonstructural Protein 13 Helicase Inhibition

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
A SAR study led to the identification of new 2‐phenylquinoline‐based derivatives that exhibit anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) activity by acting as ATP‐competitive inhibitors of nonstructural protein 13 (nsp13) helicase.
Giada Cernicchi, Maria Giulia Nizi, Roberta Emmolo, Leentje Persoons, Manon Laporte, Dirk Jochmans, Isabella Romeo, Giacomo Pepe, Ciro Milite, Pietro Campiglia, Jacopo Spezzini, Alma Martelli, Simone Brogi, Francesca Esposito, Tommaso Felicetti, Serena Massari, Giuseppe Manfroni, Stefano Sabatini, Gianluca Sbardella, Stefano Alcaro, Johan Neyts, Angela Corona, Enzo Tramontano, Steven De Jonghe, Oriana Tabarrini   +24 more
wiley   +1 more source

Replication and Injury Associated With SARS-CoV-2 in Cultured Hepatocytes

Pathogens and Immunity
Background: Liver dysfunction is one of the hallmarks of SARS-CoV-2 infection. The mechanism(s) of hepatic injury in SARS-CoV-2 infection remains controversial with some reporting viral replication and cellular injury and others suggesting lack of ...
Suman Pradhan, Susan D. Rouster, Jason T. Blackard, Gary E. Dean, Kenneth E. Sherman   +4 more
doaj   +1 more source

RC-IAL cell line: sensitivity of rubella virus grow Linhagem celular RC-IAL: sensibilidade de crescimento do vírus da rubéola

Revista de Saúde Pública, 2000
OBJECTIVE: The rapid growth of the rubella virus in RC-IAL² with development of cytopathic effect, in response to rubella virus infection, is described. For purposes of comparison, the rubella virus RA-27/3 strain was titered simultaneously in the RC-IAL,
Cristina A Figueiredo, Maria I Oliveira, Suely P Curti, Aurea S Cruz, Eliane Moreira, Ana MS Afonso, Luís Florêncio de Salles-Gomes   +6 more
doaj   +1 more source

Langat Virus Biology and Infection

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova, Daniel Sauter, Michael Schindler, Thomas Iftner   +3 more
wiley   +1 more source

Viral Disease Histopathology in Aquaculture Finfish: Organ‐Specific Pathological Changes and Diagnostic Insights, Referencing the World Organisation for Animal Health: A Review

Reviews in Aquaculture, Volume 18, Issue 2, March 2026.
ABSTRACT The aquaculture industry faces significant challenges from viral diseases, many of which are listed by the World Organisation for Animal Health (WOAH) as priority pathogens due to their impact on global finfish health and production. This review synthesizes current knowledge on the histopathology of key WOAH‐listed viral pathogens, including ...
Ram Babu Kurapati, Grace Ramena, Humphrey Wanjala, Sharon Gudapati, Yathish Ramena   +4 more
wiley   +1 more source