Results 31 to 40 of about 5,295 (175)

Early transcriptional response in the jejunum of germ-free piglets after oral infection with virulent rotavirus [PDF]

, 2008
Germ-free piglets were orally infected with virulent rotavirus to collect jejunal mucosal scrapings at 12 and 18 hours post infection (two piglets per time point).
Hulst, M.M., Wit, A.A.C., de, van der Meulen, J., Niewold, T., Meulen, J., van der, de Wit, A.A.C., Smits, M.A., Kerstens, H.H.D.   +7 more
core   +1 more source

A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors** [PDF]

, 2021
The COVID-19 pathogen, SARS-CoV-2, requires its main protease (SC2MPro ) to digest two of its translated long polypeptides to form a number of mature proteins that are essential for viral replication and pathogenesis. Inhibition of this vital proteolytic
Xu, Shiqing, Lauren R. Blankenship, Carol A. Fierke, Aleksandra K. Drelich, Yugendar R. Alugubelli, Xinyu R. Ma, Sankaran, Banumathi, Tseng, Chien‐Te K, Jin Liu, Ward, Hannah E, Liu, Wenshe Ray, R., Xinyu, Banumathi Sankaran, Li, Pingwei, Zhao, Baoyu, Jason C. Hsu, Yuying Ma, Kratch, Kaci C, Yang, Kai S, Danielle A. Scott, Hamed S. Hayatshahi, Kai S. Yang, Ma, Yuying, Hsu, Jason C, Wenshe Ray Liu, Liu, Jin, Alugubelli, Yugendar R, Fierke, Carol A, Hannah E. Ward, Pingwei Li, Chien‐Te K. Tseng, Sheng, Yan J, Geng, Zhi Z, Kaci C. Kratch, Scott, Danielle A, Blankenship, Lauren R, Zhi Z. Geng, Baoyu Zhao, Vatansever, Erol C, Hayatshahi, Hamed S, Shiqing Xu, Drelich, Aleksandra K, Erol C. Vatansever, Yan J. Sheng   +43 more
core   +1 more source

COMPARATIVE CHARACTERISTICS OF THE DEVELOPMENT OF INFLUENZA INFECTION IN MACROPHAGES DIFFERENTIATED FROM MONOCYTES OF THP-1 (INFLUENZA A VIRUSES OF SUBTYPES H1, H5 AND H9)

Инфекция и иммунитет, 2018
Macrophages (Mf) play an important role in the pathogenesis of influenza infection, but the obtaining of Mf in large quantities is difficult. In connection with this, in the present study, THP-1 monocytes differentiated by phorbol ether (PMA) into ...
T. M. Sokolova, V. V. Poloskov, A. N. Shuvalov, I. A. Rudneva, T. A. Timofeeva, R. R. Klimova, O. V. Masalova, A. A. Kushch   +7 more
doaj   +1 more source

Immunocorrective and Antiviral Activity of Polysaccharide from Marine Bacteria Against Tick-Borne Encephalitis Virus

Антибиотики и Химиотерапия, 2020
The aim of this study was to examine the immunocorrective and antiviral activity of extracellular polysaccharide (EPS) from the marine bacteria Pseudoalteromonas nigrifaciens against tick-borne encephalitis virus (TBEV). Materials and Methods.
N. V. Krylova, T. P. Smolina, M. V. Berlizova, G. N. Leonova   +3 more
doaj   +1 more source

Isolation and Identification of Two Clinical Strains of the Novel Genotype Enterovirus E5 in China

Microbiology Spectrum, 2022
Most enterovirus (EV) infections are subclinical but, occasionally, can cause severe and potentially fatal diseases in humans and animals. Currently, EVs are divided into 12 types (A to L) based on phylogenetic analysis and on their natural hosts. Bovine
Chengyuan Ji, Yao Zhang, Ruini Sun, Zihao Pan, Jiale Ma, Huochun Yao   +5 more
doaj   +1 more source

Influence of glutathione availability on cell damage induced by human immunodeficiency virus type 1 viral protein R [PDF]

, 2016
The human immunodeficiency virus type 1 (HIV-1) encodes for accessory viral protein R (Vpr), which arrests the cell cycle of host cells at G2 and causes mitochondrial dysfunction and alterations in glycolysis.
Monroy, Noemi, Herrero, Laura, Gonzalez Portal, Maria Eugenia, Carrasco, Luis   +3 more
core   +1 more source

Rift Valley Fever Virus Propagates in Human Villous Trophoblast Cell Lines and Induces Cytokine mRNA Responses Known to Provoke Miscarriage

Viruses, 2021
The mosquito-borne Rift Valley fever (RVF) is a prioritised disease that has been listed by the World Health Organization for urgent research and development of counteraction.
Yong-Dae Gwon, Seyed Alireza Nematollahi Mahani, Ivan Nagaev, Lucia Mincheva-Nilsson, Magnus Evander   +4 more
doaj   +1 more source

neutrophils are on the payroll [PDF]

, 2015
Viral hemorrhagic fever caused by hantaviruses is an emerging infectious disease for which suitable treatments are not available. In order to improve this situation a better understanding of hantaviral pathogenesis is urgently required.
Schönrich, Günther, Krüger, Detlev H., Raftery, Martin J.   +2 more
core   +1 more source

Hypertrophic genital herpes in an HIV-infected female patient: Imiquimod as an alternative treatment

International Journal of Infectious Diseases, 2020
Herpes Simplex Virus (HSV) is the leading cause of genital ulcers worldwide. In Human Immunodeficiency Virus (HIV) co-infected individuals, rare hypertrophic pseudo-tumoral forms have been described as simulating squamous cell carcinoma or other viral ...
Helena Lucia Barroso dos Reis, Neide Aparecida Tosato Boldrini, Luisa Cardoso da Silva Campos, Letícia Goulart Campos, Franco Luis Salume Costa, João Victor Jacomele Caldas, Susana Lamara Pedras Almeida, Angelica Espinosa Miranda   +7 more
doaj   +1 more source

Life cycle heterogeneity in animal models of human papillomavirus-associated disease

, 2002
Animal papillomaviruses are widely used as models to study papillomavirus infection in humans despite differences in genome organization and tissue tropism. Here, we have investigated the extent to which animal models of papillomavirus infection resemble
Peh, W.L., Liu, W.J., Christensen, N., Egawa, K., Lewis, J., Christensen, Neil, Peh, Woei Ling, Egawa, Kiyofumi, Percival, Alan, Lewis, Jon, Liu, Wen Jun, Percival, A., Nicholls, Philip, Doorbar, J., Brandsma, Janet, Middleton, K., Nicholls, P.K., Brandsma, J., Middleton, Kate, Sotlar, Karl, Sotlar, K., Doorbar, John   +21 more
core   +1 more source