Results 21 to 30 of about 5,331 (138)

Apigenin Restricts FMDV Infection and Inhibits Viral IRES Driven Translational Activity

Viruses, 2015
Foot-and-mouth disease (FMD) is a highly contagious disease of domestic and wild ruminants that is caused by FMD virus (FMDV). FMD outbreaks have occurred in livestock-containing regions worldwide.
Suhong Qian, Wenchun Fan, Ping Qian, Dong Zhang, Yurong Wei, Huanchun Chen, Xiangmin Li   +6 more
doaj   +1 more source

Possibilities of suppressing the cytopathogenic effect of SARS-CoV-2 coronavirus according to the results of the antiviral activity of Cytovir®-3 in vitro study

Антибиотики и Химиотерапия, 2021
Introduction. The COVID-19 pandemic has stimulated the search for drugs with specific antiviral activity against the new pathogenic strain of the SARS-CoV-2 coronavirus. First of all, scientific search was aimed at studying drugs with already proven efficacy
V. S. Smirnov, I. A. Leneva, T. A. Kudryavtseva, E. B. Fayzuloev, V. A. Zaplutanov, S. V. Petlenko, N. P. Kartashova, A. V. Gracheva, E. R. Korchevaya   +8 more
doaj   +1 more source

Experimental Justification of Reprofiling of the Drug Maxar® for the Treatment of Viral Infections

Антибиотики и Химиотерапия, 2023
Relevance. The development of highly effective broad-spectrum antiviral agents is one of the priorities in medicine, virology, and pharmacology. The strategy of repurposing (repositioning) registered drugs is of special interest along with significant ...
T. S. Zaporozhets, N. V. Krylova, S. A. Fedoreyev, O. V. Iunikhina, A. B. Pott, D. V. Tarbeeva, N. P. Mishchenko, M. Yu. Shchelkanov   +7 more
doaj   +1 more source

Epidemiology of Marek's Disease Virus Type 2 and the Molecular and Pathology Characterization of Virus Isolates in China (2015-2024). [PDF]

Transbound Emerg Dis
Marek’s disease (MD) continues to cause significant economic losses in the global poultry industry. During routine MD surveillance in China, MD virus type 2 (MDV‐2), which has the potential for widespread dissemination, was detected. In this study, 2842 suspected MD samples were collected from 237 poultry flocks vaccinated against MD across 21 ...
Lin Y, Hu M, Wu C, Lu H, Chen M, Liu C, Cui H, Liu Y, Qi X, Wang S, Chen Y, Duan Y, Gao Y, Zhang Y.   +13 more
europepmc   +2 more sources

Inhibition of enterovirus 71 replication and viral 3C protease by quercetin

Virology Journal, 2018
Background Enterovirus 71 (EV71) is one of the major causative agents of hand, foot, and mouth disease (HFMD), which is sometimes associated with severe central nervous system disease in children.
Chenguang Yao, Caili Xi, Kanghong Hu, Wa Gao, Xiaofeng Cai, Jinlan Qin, Shiyun Lv, Canghao Du, Yanhong Wei   +8 more
doaj   +1 more source

Evaluation of Antiviral, Antibacterial and Antiproliferative Activities of the Endophytic Fungus Curvularia papendorfii, and Isolation of a New Polyhydroxyacid

Microorganisms, 2020
An endophytic fungus isolated from Vernonia amygdalina, a medicinal plant from Sudan, was taxonomically characterized as Curvularia papendorfii. Ethyl acetate crude extract of C.
Afra Khiralla, Rosella Spina, Mihayl Varbanov, Stéphanie Philippot, Pascal Lemiere, Sophie Slezack-Deschaumes, Philippe André, Ietidal Mohamed, Sakina Mohamed Yagi, Dominique Laurain-Mattar   +9 more
doaj   +1 more source

COMPARATIVE CHARACTERISTICS OF THE DEVELOPMENT OF INFLUENZA INFECTION IN MACROPHAGES DIFFERENTIATED FROM MONOCYTES OF THP-1 (INFLUENZA A VIRUSES OF SUBTYPES H1, H5 AND H9)

Инфекция и иммунитет, 2018
Macrophages (Mf) play an important role in the pathogenesis of influenza infection, but the obtaining of Mf in large quantities is difficult. In connection with this, in the present study, THP-1 monocytes differentiated by phorbol ether (PMA) into ...
T. M. Sokolova, V. V. Poloskov, A. N. Shuvalov, I. A. Rudneva, T. A. Timofeeva, R. R. Klimova, O. V. Masalova, A. A. Kushch   +7 more
doaj   +1 more source

Immunocorrective and Antiviral Activity of Polysaccharide from Marine Bacteria Against Tick-Borne Encephalitis Virus

Антибиотики и Химиотерапия, 2020
The aim of this study was to examine the immunocorrective and antiviral activity of extracellular polysaccharide (EPS) from the marine bacteria Pseudoalteromonas nigrifaciens against tick-borne encephalitis virus (TBEV). Materials and Methods.
N. V. Krylova, T. P. Smolina, M. V. Berlizova, G. N. Leonova   +3 more
doaj   +1 more source

Isolation and Identification of Two Clinical Strains of the Novel Genotype Enterovirus E5 in China

Microbiology Spectrum, 2022
Most enterovirus (EV) infections are subclinical but, occasionally, can cause severe and potentially fatal diseases in humans and animals. Currently, EVs are divided into 12 types (A to L) based on phylogenetic analysis and on their natural hosts. Bovine
Chengyuan Ji, Yao Zhang, Ruini Sun, Zihao Pan, Jiale Ma, Huochun Yao   +5 more
doaj   +1 more source

Rift Valley Fever Virus Propagates in Human Villous Trophoblast Cell Lines and Induces Cytokine mRNA Responses Known to Provoke Miscarriage

Viruses, 2021
The mosquito-borne Rift Valley fever (RVF) is a prioritised disease that has been listed by the World Health Organization for urgent research and development of counteraction.
Yong-Dae Gwon, Seyed Alireza Nematollahi Mahani, Ivan Nagaev, Lucia Mincheva-Nilsson, Magnus Evander   +4 more
doaj   +1 more source