Results 1 to 10 of about 9,861,124 (177)

Efficacy, Safety and Biological Characteristics of Formulation Based on Essential Oil Against Co-Infections of Herpes Simplex Virus-1 and Candida albicans. [PDF]

Microbiologyopen
Essential oils with anti‐HSV‐1 activity were identified through literature review and tested against Candida to develop a formulation for co‐infections. The blend was assessed for anti‐inflammatory properties, allergenic potential via standardized BAT, and overall antiviral efficacy.
Di Vito M, Coggiatti D, La Sorda M, Garzoli S, Lombardini G, Talamonti D, Pizzarelli S, Zhiri A, Cacaci M, Torelli R, Sanguinetti M, Bugli F.   +11 more
europepmc   +2 more sources

B-Cell Depletion Relative to Tumor Necrosis Factor Inhibition Extends the Duration of Viral Shedding in COVID-19 Among Autoimmune Disease Patients: A Matched Prospective Cohort Study. [PDF]

ACR Open Rheumatol
Objective To investigate SARS‐CoV‐2 viral shedding duration in autoimmune patients using B cell depleting (BCD) therapy or tumor necrosis factor inhibitors (TNFi) and immunocompetent comparators. Methods We conducted a matched cohort analysis among participants in POSITIVES, a prospective study enrolling outpatients with acute COVID‐19 within five days
Getachew LS, Wang X, Patel NJ, Wallace ZS, O'Keeffe LA, Negron M, Wang J, Qian G, Saavedra AA, Mueller KT, Davis N, Li Y, Leeman BM, Choudhary MC, Haneuse S, Benz L, Boucau J, Edelstein GE, Glover OT, Kawano Y, Deo R, Reynolds Z, Su K, Mandell CB, Smith-Sparks Z, Passell E, Barry MO, Tien D, Hammond SP, Gaiha GD, Lemieux JE, Barczak AK, Li JZ, Siedner MJ, Sparks JA.   +34 more
europepmc   +2 more sources

A trans-activating transduction peptide fused nanobody targeting viral nonstructural protein NS4B inhibits bovine viral diarrhea virus replication [PDF]

Frontiers in Immunology
IntroductionBovine viral diarrhea virus (BVDV) is a major pathogen in cattle globally. Nanobodies (Nbs) possess attractive therapeutic properties, but their efficacy against intracellular targets like BVDV is hindered by poor membrane permeability ...
Bao Zhao, Bao Zhao, Bao Zhao, Zehao Lv, Zehao Lv, Wenqi Fan, Wenqi Fan, Ying Zhang, Ying Zhang, Shuang Wei, Shuang Wei, Junyang Fang, Junyang Fang, Ni Huang, Ni Huang, Xiwen Chen, Lizhen Wang, Lizhen Wang, Xuefeng Qi, Xuefeng Qi   +19 more
doaj   +2 more sources

Mpox in South Asia: A Narrative Review on Epidemiology, Preparedness, and Preventive Strategies. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Monkeypox (Mpox), due to its growing global concern, was declared a public health emergency of worldwide concern by the World Health Organization in August 2024. The monkeypox virus (MPXV), once limited to African regions, has now spread to South Asia, including Pakistan, India, Nepal, and Sri Lanka, and there have been ...
Mawa J, Rimun SN, Rahman NZ, Bhuiyan MA, Shahriar M, Anjum R.   +5 more
europepmc   +2 more sources

The Effect of Bovine Viral Diarrhoea Virus Biotypes on Bovine Oocyte In Vitro. [PDF]

Vet Med Sci
Bovine viral diarrhoea virus (BVDV) is a significant pathogen with two biotypes, cytopathic (CP) and non‐cytopathic (NCP). The aims were to examine the impact of BVDV on the expression of genes related to apoptosis and total antioxidant capacity (TAC) in vitro. Oocytes were infected with two BVDV biotypes.
Roshanzamir A, Talebkhan Garoussi M, Mehrzad J.   +2 more
europepmc   +2 more sources

Novel Cost-Efficient Graphene-Based Impedance Biosensor for the Analysis of Viral Cytopathogenicity and the Effect of Antiviral Drugs [PDF]

Frontiers in Bioengineering and Biotechnology, 2021
Biosensors become increasingly relevant for medical diagnostics, pharmaceutical industry, and environmental technology, for example, to test new drugs easily and reliably or to detect cell growth in changing environmental conditions. Novel materials like graphene are promising candidates to produce biosensors on an industrial scale by means of printing
Anke Schultz, Thorsten Knoll, Andreas Urban, Herbert Schuck, Hagen von Briesen, Anja Germann, Thomas Velten   +6 more
openaire   +3 more sources

Atypical perianal and buttocks epidermal-dermal necrosis in Human Monkeypox. Histopathological study of the lesion in Peru

Anales de la Facultad de Medicina, 2023
We report the histopathological study of a large, black, crusted lesion with symmetrical distribution in both buttocks and perineum, never described, in a man who has sex with men (MSM) and proctitis associated with Human Monkey Pox Virus (hMPXV) and HIV-
Luis E. Terry Castellano, Víctor Delgado Gonzáles, Luis Saúl J. Terry Ulloa   +2 more
doaj   +1 more source

Experimental bluetongue virus infection of Culicoides austropalpalis, collected from a farm environment in Victoria, Australia

Veterinaria Italiana, 2021
Following the emerging bluetongue virus transmission in European temperate regions, we question the vector competence of the abundant Culicoides austropalpalis Lee and Reye in South-East temperate Australia.
Jean-Bernard Duchemin, John R White, Antonio Di Rubbo, Shunin Shi, Gert Johannes Venter, Ian Holmes, Peter J Walker   +6 more
doaj   +1 more source

Comparison of the Ability of High and Low Virulence Strains of Non-cytopathic Bovine Viral Diarrhea Virus-1 to Modulate Expression of Interferon Tau Stimulated Genes in Bovine Endometrium

Frontiers in Veterinary Science, 2021
Bovine Viral Diarrhea virus (BVDV) is a pestivirus with a single-stranded, positive sense RNA genome. It is endemic in many cattle populations, causing major economic losses in part due to reduced fertility.
Kai Wang, Kai Wang, Carole Thomas, Shujun Zhang, D. Claire Wathes, Zhangrui Cheng   +5 more
doaj   +1 more source

Virucidal and virostatic in vitro activity of ELOM-080 against respiratory pathogens

Phytomedicine Plus, 2021
Background: The herbal medicinal product (HMP) ELOM-080 has a proven efficacy in the treatment of acute respiratory tract (ART) infections, which typically are of viral etiology.
Jörn Thomsen, Kristina Röschmann-Doose, Thomas Wittig, Karin Kraft   +3 more
doaj   +1 more source