Results 121 to 130 of about 1,300,822 (378)

Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial Cytoplasm

PLoS Comput. Biol., 2010
A longstanding question in molecular biology is the extent to which the behavior of macromolecules observed in vitro accurately reflects their behavior in vivo.
S. McGuffee, A. Elcock
semanticscholar   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

PCR identification of Petunia male sterile cytoplasm

Ornamental Horticulture, 2019
Petunia is a very important ornamental plant with a broad range of flower colour and size, and most of the cultivars grown are propagated through seeds.
Noemí Colombo, Juan Carlos Hagiwara
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability

eLife
Autophagy-related gene 6 (ATG6) plays a crucial role in plant immunity. Nonexpressor of pathogenesis-related genes 1 (NPR1) acts as a signaling hub of plant immunity. However, the relationship between ATG6 and NPR1 is unclear.
Baihong Zhang, Shuqin Huang, Shuyu Guo, Yixuan Meng, Yuzhen Tian, Yue Zhou, Hang Chen, Xue Li, Jun Zhou, Wenli Chen   +9 more
doaj   +1 more source

Novel CMS lines in pigeonpea [Cajanus cajan (L.) Millspaugh] derived from cytoplasmic substitutions, and their effective restoration and deployment in hybrid breeding

Crop Journal, 2017
The availability of stable cytoplasmic male sterile (CMS or A) lines coupled with a robust restoration system (R lines) is an essential prerequisite for efficient hybrid breeding.
Abhishek Bohra, Rintu Jha, Indra Prakash Singh, Gaurav Pandey, Shalini Pareek, Partha Sarathi Basu, Sushil Kumar Chaturvedi, Narendra Pratap Singh   +7 more
doaj   +1 more source

Lariat intronic RNAs in the cytoplasm of Xenopus tropicalis oocytes

RNA: A publication of the RNA Society, 2014
Deep sequencing of cytoplasmic RNA from the oocyte of the frog Xenopus reveals a population of stable lariat molecules derived from specific introns of several thousand protein-coding genes.
Gaëlle J S Talhouarne, J. Gall
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Hallazgos histológicos de inmunohistoquímica y ultraestructura en hiperplasia epitelial focal

Ciencia Ergo Sum, 2000
Se estudiaron 22 biopsias de ...
Blanca Silvia González López
doaj  

Morphopathology of the Prussian carp (Carassius auratus gibelio Bloch, 1782) liver under the effect of allyl acetate

Ribogospodarsʹka Nauka Ukraïni
Purpose. To assess the liver parenchyma of Prussian carp based on the analysis of histological parameters of the organ, to establish the level of the effect of alylacetate on the physiological status of fish and the degree of their damage.
M. Koziy
doaj   +1 more source