Results 151 to 160 of about 1,300,822 (378)
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Hormonal influences on the incorporation of injected precursors into the protein and ribonucleic acid of liver cytoplasm [PDF]
, 1956 E. Emmet Reid +3 more
openalex +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Heliyon, 2021 Advances in research resulted in development of a simple, rapid and reliable multiplex PCR protocol for cytoplasm differentiation in potato. Applying this rapid technique, we assessed the cytoplasm diversity in 57 Indian potato varieties, 15 popular ...
Salej Sood +4 more
doaj
General introduction to cytoplasm
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1969 A mere glance at figures 1 and 2 is enough to demonstrate, in a schematic way, how different our present understanding of cell structure is from that of E. B. Wilson, some 40 years ago: while the essential constituents of the cell nucleus were already known, the cytoplasm had an alveolar (or fibrillar) structure, where no cell organelles (besides the ...
openaire +4 more sources
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Plant Production Science, 2002 The msm 1 and msm 2 cytoplasms cause male sterility in barley. In order to clarify whether these cytoplasms can be used for hybrid seed production in Japan, we investigated the fertility restoration under environmental conditions in Japan using ...
Katsuhiro Matsui +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Age- and AD-related redox state of NADH in subcellular compartments by fluorescence lifetime imaging microscopy. [PDF]
, 2019 Nicotinamide adenine dinucleotide (reduced form: NADH) serves as a vital redox-energy currency for reduction-oxidation homeostasis and fulfilling energetic demands.
Brewer, Gregory J +2 more
core +1 more source