Results 181 to 190 of about 1,653,701 (332)
TDP‐43 and FUS en route from the nucleus to the cytoplasm
H. Ederle, D. Dormann
semanticscholar +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Mobility of ions, sugar, and water in the cytoplasm of Xenopus oocytes expressing Na+‐coupled sugar transporters (SGLT1) [PDF]
Thomas Zeuthen +2 more
openalex +1 more source
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
To determine the cytological criteria that allow prediction of occurrence and course of inflammation of the oral mucosa and periodontal tissues, we performed cytological study of buccal epithelium of young people who have the habit smoking.
N.V. Gasiuk, T.N. Moshel, I.Yu. Popovich
doaj
Low viscosity in the aqueous domain of cell cytoplasm measured by picosecond polarization microfluorimetry. [PDF]
Kiyohide Fushimi, A.S. Verkman
openalex +1 more source
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source

