Mobility of Min-proteins in Escherichia coli measured by fluorescence correlation spectroscopy [PDF]
In the bacterium Escherichia coli, selection of the division site involves pole-to-pole oscillations of the proteins MinD and MinE. Different oscillation mechanisms based on cooperative effects between Min-proteins and on the exchange of Min-proteins between the cytoplasm and the cytoplasmic membrane have been proposed.
arxiv +1 more source
SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2. [PDF]
SIRT1 and SIRT3 are NAD+-dependent protein deacetylases that are evolutionarily conserved across mammals. These proteins are located in the cytoplasm/nucleus and mitochondria, respectively.
Capra, John A+4 more
core +3 more sources
The tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to regulate transcription of genes involved in processes including cell cycle arrest, DNA repair, and apoptosis. Nevertheless, recent papers show that p53 may have a separate cytoplasmic role in directly regulating the Bax-dependent mitochondrial pathway to cell ...
Nicole Baptiste, Carol Prives
openaire +3 more sources
Pattern formation at cellular membranes by phosphorylation and dephosphorylation of proteins [PDF]
We consider a classical model on activation of proteins, based in two reciprocal enzymatic biochemical reactions. The combination of phosphorylation and dephosphorylation reactions of proteins is a well established mechanism for protein activation in ...
Alonso Muñoz, Sergio
core +2 more sources
Spatial control of irreversible protein aggregation [PDF]
Liquid cellular compartments spatially segregate from the cytoplasm and can regulate aberrant protein aggregation, a process linked to several medical conditions, including Alzheimer's and Parkinson's diseases.
Mahadevan, L.+2 more
core +2 more sources
Magnetic wire as stress controlled micro-rheometer for cytoplasm viscosity measurements [PDF]
We review here different methods to measure the bulk viscosity of complex fluids using micron-sized magnetic wires. The wires are characterized by length of a few microns and diameter of a few hundreds of nanometers.
Berret, Jean-Francois
core +3 more sources
An interpenetrating-network theory of cytoplasm [PDF]
Under many physiological and pathological conditions such as division and migration, cells undergo dramatic deformations, under which their mechanical integrity is supported by cytoskeletal networks (i.e. intermediate filaments, F-actin, and microtubules).
arxiv
Confocal Raman data analysis enables identifying apoptosis of MCF-7 cells caused by anticancer drug paclitaxel [PDF]
Confocal Raman microscopy is a noninvasive, label-free imaging technique used to study apoptosis of live MCF-7 cells. The images are based on Raman spectra of cells components, and their apoptosis is monitored through diffusion of cytochrome c in ...
Attila-Gergely Vegh+7 more
core +1 more source
Glassy dynamics of a model of bacterial cytoplasm with metabolic activities [PDF]
Recent experiments have revealed that cytoplasms become glassy when their metabolism is suppressed, while they maintain fluidity in a living state. The mechanism of this active fluidization is not clear, especially for bacterial cytoplasms, since they lack traditional motor proteins, which can cause directed motions.
arxiv +1 more source
Expression of the gene for main intrinsic polypeptide (MIP): separate spatial distributions of MIP and beta-crystallin gene transcripts in rat lens development [PDF]
The main intrinsic polypeptide (MIP) is the major protein present in the lens fiber cell membrane and is the product of a gene which, as far as is known, is expressed only in the lens.
Chung, Johnson+3 more
core +1 more source