Results 31 to 40 of about 1,300,822 (378)
Undervalued ubiquitous proteins
The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source
SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2. [PDF]
SIRT1 and SIRT3 are NAD+-dependent protein deacetylases that are evolutionarily conserved across mammals. These proteins are located in the cytoplasm/nucleus and mitochondria, respectively.
Capra, John A+4 more
core +3 more sources
Superdiffusion dominates intracellular particle motion in the supercrowded cytoplasm of pathogenic Acanthamoeba castellanii [PDF]
Acanthamoebae are free-living protists and human pathogens, whose cellular functions and pathogenicity strongly depend on the transport of intracellular vesicles and granules through the cytosol.
Julia F. Reverey+5 more
semanticscholar +1 more source
How bulk cytoplasm generates forces to separate post-anaphase microtubule (MT) asters in Xenopus laevis and other large eggs remains unclear. Previous models proposed that dynein-based, inward organelle transport generates length-dependent pulling forces
James F Pelletier+4 more
doaj +1 more source
Marker-assisted breeding of onion (A. cepa L.) maintainer line resistant to Downy mildew
Relevance. F1 hybrids breeding programs of onion are based on the use of nuclear cytoplasmic male sterility (NCMS). Breeding and seed production based on NCMS suggest a development of a female sterile maternal line, a maintainer line and a paternal ...
Ya. T. Eidlin+2 more
doaj +1 more source
Intracellular mechanochemical waves in an active poroelastic model [PDF]
Many processes in living cells are controlled by biochemical substances regulating active stresses. The cytoplasm is an active material with both viscoelastic and liquid properties. We incorporate the active stress into a two-phase model of the cytoplasm
Alonso Muñoz, Sergio+3 more
core +2 more sources
Protein clustering in chemically stressed HeLa cells studied by infrared nanospectroscopy [PDF]
Photo-Thermal Induced Resonance (PTIR) nanospectroscopy, tuned towards amide-I absorption, was used to study the distribution of proteic material in 34 different HeLa cells, of which 18 were chemically stressed by oxidative stress with Na3AsO3.
BALDASSARRE, Leonetta+6 more
core +1 more source
The tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to regulate transcription of genes involved in processes including cell cycle arrest, DNA repair, and apoptosis. Nevertheless, recent papers show that p53 may have a separate cytoplasmic role in directly regulating the Bax-dependent mitochondrial pathway to cell ...
Nicole Baptiste, Carol Prives
openaire +3 more sources
Lariat intronic RNAs in the cytoplasm of vertebrate cells
Significance Introns are noncoding DNA sequences interspersed among the coding sequences of genes. Shortly after transcription, the intronic sequences are spliced out of the primary RNA transcript as lariat RNAs (circular molecules with a short tail ...
Gaëlle J S Talhouarne, J. Gall
semanticscholar +1 more source
Spatial control of irreversible protein aggregation [PDF]
Liquid cellular compartments spatially segregate from the cytoplasm and can regulate aberrant protein aggregation, a process linked to several medical conditions, including Alzheimer's and Parkinson's diseases.
Mahadevan, L.+2 more
core +2 more sources