Results 31 to 40 of about 1,300,822 (378)

Undervalued ubiquitous proteins

open access: yes4 open, 2019
The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2. [PDF]

open access: yes, 2011
SIRT1 and SIRT3 are NAD+-dependent protein deacetylases that are evolutionarily conserved across mammals. These proteins are located in the cytoplasm/nucleus and mitochondria, respectively.
Capra, John A   +4 more
core   +3 more sources

Superdiffusion dominates intracellular particle motion in the supercrowded cytoplasm of pathogenic Acanthamoeba castellanii [PDF]

open access: yesScientific Reports, 2015
Acanthamoebae are free-living protists and human pathogens, whose cellular functions and pathogenicity strongly depend on the transport of intracellular vesicles and granules through the cytosol.
Julia F. Reverey   +5 more
semanticscholar   +1 more source

Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm

open access: yeseLife, 2020
How bulk cytoplasm generates forces to separate post-anaphase microtubule (MT) asters in Xenopus laevis and other large eggs remains unclear. Previous models proposed that dynein-based, inward organelle transport generates length-dependent pulling forces
James F Pelletier   +4 more
doaj   +1 more source

Marker-assisted breeding of onion (A. cepa L.) maintainer line resistant to Downy mildew

open access: yesОвощи России, 2021
Relevance. F1 hybrids breeding programs of onion are based on the use of nuclear cytoplasmic male sterility (NCMS). Breeding and seed production based on NCMS suggest a development of a female sterile maternal line, a maintainer line and a paternal ...
Ya. T. Eidlin   +2 more
doaj   +1 more source

Intracellular mechanochemical waves in an active poroelastic model [PDF]

open access: yes, 2013
Many processes in living cells are controlled by biochemical substances regulating active stresses. The cytoplasm is an active material with both viscoelastic and liquid properties. We incorporate the active stress into a two-phase model of the cytoplasm
Alonso Muñoz, Sergio   +3 more
core   +2 more sources

Protein clustering in chemically stressed HeLa cells studied by infrared nanospectroscopy [PDF]

open access: yes, 2016
Photo-Thermal Induced Resonance (PTIR) nanospectroscopy, tuned towards amide-I absorption, was used to study the distribution of proteic material in 34 different HeLa cells, of which 18 were chemically stressed by oxidative stress with Na3AsO3.
BALDASSARRE, Leonetta   +6 more
core   +1 more source

p53 in the Cytoplasm [PDF]

open access: yesCell, 2004
The tumor suppressor p53 regulates cellular responses to stress by serving in the nucleus to regulate transcription of genes involved in processes including cell cycle arrest, DNA repair, and apoptosis. Nevertheless, recent papers show that p53 may have a separate cytoplasmic role in directly regulating the Bax-dependent mitochondrial pathway to cell ...
Nicole Baptiste, Carol Prives
openaire   +3 more sources

Lariat intronic RNAs in the cytoplasm of vertebrate cells

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Introns are noncoding DNA sequences interspersed among the coding sequences of genes. Shortly after transcription, the intronic sequences are spliced out of the primary RNA transcript as lariat RNAs (circular molecules with a short tail ...
Gaëlle J S Talhouarne, J. Gall
semanticscholar   +1 more source

Spatial control of irreversible protein aggregation [PDF]

open access: yes, 2018
Liquid cellular compartments spatially segregate from the cytoplasm and can regulate aberrant protein aggregation, a process linked to several medical conditions, including Alzheimer's and Parkinson's diseases.
Mahadevan, L.   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy