Results 51 to 60 of about 1,064,976 (259)

The cytoplasm of living cells can sustain transient and steady intracellular pressure gradients

eLife
Understanding the physical basis of cellular shape change in response to both internal and external mechanical stresses requires characterisation of cytoplasmic rheology.
Majid Malboubi, Mohammad Hadi Esteki, Malti B Vaghela, Lulu IT Korsak, Ryan J Petrie, Emad Moeendarbary, Guillaume Charras   +6 more
doaj   +1 more source

Threshold estimation based on local minima for nucleus and cytoplasm segmentation

BMC Medical Imaging, 2022
Background Image segmentation is the process of partitioning an image into separate objects or regions. It is an essential step in image processing to segment the regions of interest for further processing.
Simeon Mayala, Jonas Bull Haugsøen
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

A novel cytosolic NADH:quinone oxidoreductase from Methanothermobacter marburgensis

Bioscience Reports, 2014
Methanothermobacter marburgensis is a strictly anaerobic, thermophilic methanogenic archaeon that uses methanogenesis to convert H2 and CO2 to energy. M.
Eva Ullmann, Tien Chye Tan, Thomas Gundinger, Christoph Herwig, Christina Divne, Oliver Spadiut   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Dissecting the disconnect between circuit activation and dominant adaptive evolution in cytoplasmic phage-assisted continuous evolution (PACE) of an EGFR nanobody

Frontiers in Bioengineering and Biotechnology
IntroductionCytoplasmic phage-assisted continuous evolution (PACE) is widely used due to its low selection pressure and straightforward circuit design.
Jie-Ning Chuang, Jacob Purcell, Loki Sangalli, Joseph Rosenbluh, Gavin J. Knott, Gavin J. Knott, Simon Corrie, Gil Garnier   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Etymologia: Histoplasma capsulatum

Emerging Infectious Diseases, 2021
Monika Mahajan
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Morphopathology of the Prussian carp (Carassius auratus gibelio Bloch, 1782) liver under the effect of allyl acetate

Ribogospodarsʹka Nauka Ukraïni
Purpose. To assess the liver parenchyma of Prussian carp based on the analysis of histological parameters of the organ, to establish the level of the effect of alylacetate on the physiological status of fish and the degree of their damage.
M. Koziy
doaj   +1 more source