Results 41 to 50 of about 1,309,246 (380)

Spatial control of irreversible protein aggregation [PDF]

open access: yes, 2018
Liquid cellular compartments spatially segregate from the cytoplasm and can regulate aberrant protein aggregation, a process linked to several medical conditions, including Alzheimer's and Parkinson's diseases.
Mahadevan, L.   +2 more
core   +2 more sources

Biomolecular interactions modulate macromolecular structure and dynamics in atomistic model of a bacterial cytoplasm

open access: yeseLife, 2016
Biological macromolecules function in highly crowded cellular environments. The structure and dynamics of proteins and nucleic acids are well characterized in vitro, but in vivo crowding effects remain unclear.
I. Yu   +6 more
semanticscholar   +1 more source

Additivities for Soluble Recombinant Protein Expression in Cytoplasm of Escherichia coli

open access: yesFermentation
Recombinant protein expression in Escherichia coli is a fundamental technique in molecular biology and biotechnology. This review provides a comprehensive overview of various additivities to enhance the expression levels of soluble recombinant proteins ...
Denis L. Atroshenko   +3 more
doaj   +1 more source

Cell nuclei have lower refractive index and mass density than cytoplasm

open access: yesJournal of Biophotonics, 2016
Common perception regards the nucleus as a densely packed object with higher refractive index (RI) and mass density than the surrounding cytoplasm. Here, the volume of isolated nuclei is systematically varied by electrostatic and osmotic conditions as ...
M. Schürmann   +4 more
semanticscholar   +1 more source

An Unsupervised Approach for Overlapping Cervical Cell Cytoplasm Segmentation

open access: yes, 2017
The poor contrast and the overlapping of cervical cell cytoplasm are the major issues in the accurate segmentation of cervical cell cytoplasm. This paper presents an automated unsupervised cytoplasm segmentation approach which can effectively find the ...
Chatterjee, Swarnadip   +4 more
core   +1 more source

Magnetic wire as stress controlled micro-rheometer for cytoplasm viscosity measurements [PDF]

open access: yes, 2018
We review here different methods to measure the bulk viscosity of complex fluids using micron-sized magnetic wires. The wires are characterized by length of a few microns and diameter of a few hundreds of nanometers.
Berret, Jean-Francois
core   +3 more sources

Confocal Raman data analysis enables identifying apoptosis of MCF-7 cells caused by anticancer drug paclitaxel [PDF]

open access: yes, 2013
Confocal Raman microscopy is a noninvasive, label-free imaging technique used to study apoptosis of live MCF-7 cells. The images are based on Raman spectra of cells components, and their apoptosis is monitored through diffusion of cytochrome c in ...
Attila-Gergely Vegh   +7 more
core   +1 more source

Expression of the gene for main intrinsic polypeptide (MIP): separate spatial distributions of MIP and beta-crystallin gene transcripts in rat lens development [PDF]

open access: yes, 1988
The main intrinsic polypeptide (MIP) is the major protein present in the lens fiber cell membrane and is the product of a gene which, as far as is known, is expressed only in the lens.
Chung, Johnson   +3 more
core   +1 more source

Universal glass-forming behavior of in vitro and living cytoplasm

open access: yesScientific Reports, 2017
Physiological processes in cells are performed efficiently without getting jammed although cytoplasm is highly crowded with various macromolecules. Elucidating the physical machinery is challenging because the interior of a cell is so complex and driven ...
K. Nishizawa   +5 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

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