Results 51 to 60 of about 1,082,029 (359)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Promiscuity of the Euonymus Carbohydrate-Binding Domain
Biomolecules, 2012 Plants synthesize small amounts of carbohydrate-binding proteins on exposure to stress. For example, on exposure to drought, high salt, wounding and by treatment with some plant hormones or by pathogen attack. In contrast to the ‘classical’ plant lectins
Els J.M. Van Damme, Elke Fouquaert
doaj +1 more source
Cells, 2023 The axoneme and accessory structures of flagella are critical for sperm motility and male fertilization. Sperm production needs precise and highly ordered gene expression to initiate and sustain the many cellular processes that result in mature ...
Xiuqing He +9 more
doaj +1 more source
The site of ribonucleic acid synthesis in the isolated nucleus [PDF]
, 1961 There is still controversy concerning the primary site of RNA synthesis in the cell.(1) When tissues are radioautographed after administration of radioactive inorganic phosphorus or radioactive RNA(2) precursors such as tritiated uridine or cytidine, it ...
Bonner, James, Rho, Joon H.
core
Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei [PDF]
, 2017 The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite.
Agop-Nersesian, Carolina +5 more
core +2 more sources
Salting‐in the microbial cytoplasm [PDF]
FEBS Letters, 2006 Microbial organisms are known to rely for osmotic regulatory purposes on an assortment of low molecular weight molecules earmarked for function as osmolytes. The so‐called ‘compatible’ subclass of osmolyte, notably glycine betaine, is distinguished by a propensity to avoid the large bound fraction of cytoplasmic water adsorbed at the surface of ...
openaire +3 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Fatal and Benign Congenital Myopathies: Differential Diagnosis
Pediatric Neurology Briefs, 1991 Muscle biopsies from four infants with fatal myopathy and four with benign myopathy were examined using biochemical, histochemical and immunohistochemical techniques in the Departments of Neurology, Pathology and Genetics, Columbia University, New York ...
J Gordon Millichap
doaj +1 more source
Protein Mobility in the Cytoplasm of Escherichia coli [PDF]
, 1999 The rate of protein diffusion in bacterial cytoplasm may constrain a variety of cellular functions and limit the rates of many biochemical reactions in vivo. In this paper, we report noninvasive measurements of the apparent diffusion coefficient of green
Elowitz, Michael B. +4 more
core +2 more sources
Giant cell formation produced by laser microbeam irradiation of chromatin in Chinese hamster cells [PDF]
, 1981 A pulsed laser microbeam of wavelength 532 nm was used to produce visible small lesions in the nucleoplasm or in the cytoplasm of V79 Chinese hamster cells.
Altmann +34 more
core +2 more sources