Results 51 to 60 of about 30,827 (303)

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Genetic characterisation of a novel male sterile two-type line system 19F08AB in Brassica napus L.

Czech Journal of Genetics and Plant Breeding
Rapeseed (Brassica napus L.) is a major global oilseed crop and exhibits significant heterosis. The discovery and characterisation of novel male-sterile accessions remain fundamental for harnessing heterosis in rapeseed breeding. Previously, we developed
Lirong Zhao, Zikang Chen, Ruting Xie, Hui Dong, Haibo Yu, Dongsuo Zhang, Zhaoxin Hu, Shengwu Hu   +7 more
doaj   +1 more source

Combined Transcriptome and Proteome Analysis of Anthers of AL-type Cytoplasmic Male Sterile Line and Its Maintainer Line Reveals New Insights into Mechanism of Male Sterility in Common Wheat

Frontiers in Genetics, 2021
Cytoplasmic male sterility (CMS) plays an essential role in hybrid seeds production. In wheat, orf279 was reported as a CMS gene of AL-type male sterile line (AL18A), but its sterility mechanism is still unclear.
Miaomiao Hao, Miaomiao Hao, Wenlong Yang, Wenlong Yang, Tingdong Li, Tingdong Li, Muhammad Shoaib, Muhammad Shoaib, Jiazhu Sun, Dongcheng Liu, Xin Li, Yingbin Nie, Xiaoming Tian, Aimin Zhang   +13 more
doaj   +1 more source

A rare exception to Haldane's rule: are X chromosomes key to hybrid incompatibilities? [PDF]

, 2017
This work was funded by NERC (NE/G014906/1, NE/L011255/1, NE/I027800/1). Additional funding from the Orthopterists’ Society to PM is also gratefully acknowledged.The prevalence of Haldane’s rule suggests that sex chromosomes commonly have a key role in ...
A Dey, A Qvarnström, A Telschow, A Zeileis, AD Cutter, AF Zuur, AN Brothers, AW Davis, B Charlesworth, B Mantovani, BC Phillips, C Fraïsse, C Wu, CC Laurie, CD Meiklejohn, DC Presgraves, DC Presgraves, DC Presgraves, DC Presgraves, ET Watson, F Ohmachi, GC Woodruff, H Hollocher, HA Orr, HA Orr, HA Orr, HA Orr, HA Orr, HJ Muller, J Martín-Coello, JA Coyne, JA Coyne, JA Coyne, JBS Haldane, JD Bundus, JH Malone, JL Kozlowska, JM Ranz, JP Masly, JR Spence, K Sawamura, K Sawamura, LF Delph, LW Simmons, M G Ritchie, M Schilthuizen, M Turelli, M Turelli, M Turelli, MJ Wade, N Davies, N W Bailey, NA Johnson, NA Johnson, P A Moran, P Michalak, PG Fontana, S Maheshwari, SA Frank, SE Baird, SE Baird, SR McDermott, SR Virdee, SR Virdee, T Dobzhansky, T Hothorn, T Koevoets, T Mousseau, TA Abe, TA Suzuki, TW Hogan, WN Venables, Y Tao   +72 more
core   +2 more sources

Hybrid Microdiscs for Magnetically Induced Non‐Cytotoxic Thermal Actuation and Programmable Biomolecule Delivery

Advanced Functional Materials, EarlyView.
Hybrid magnetic microdiscs with customizable size and composition are engineered through refined photolithography and LbL assembly. Embedded Fe3O4 nanoparticles enable localized, non‐cytotoxic heating, while protein cargos can be incorporated in tunable quantities.
Daniela Iglesias‐Rojas, Danny Villanueva, Jon Mentxaka‐Salgado, Nerea Lete, Ane Olazagoitia‐Garmendia, Eduardo Fernández, Iñaki Orue, Alfredo García‐Arribas, Maria Luisa Fdez‐Gubieda, Ainara Castellanos‐Rubio, Robert Morel, Bernard Dieny, Maite Insausti, Idoia Castellanos‐Rubio   +13 more
wiley   +1 more source

Cytoplasmic male sterility in barley [PDF]

Physiologia Plantarum, 1980
AbstractThe maternal male sterile barley msm1 with or without a dominant gene, Rfmla, which restores male fertility, was studied. Determined with SDS‐PAGE, the polypeptide pattern in the anthers of unrestored msm1 plants remains juvenile in the middle of anther development, two major zones being absent or weak.
openaire   +3 more sources

(Molecular analysis of cytoplasmic male sterility) [PDF]

, 1990
We have determined the actual RNA sequence of four mitochondrial genes: pcf, nad3, rps12, and coxII. Because plant mitochondrial proteins cannot be predicted from DNA sequences, the actual primary structures of the encoded proteins were unknown. We have gained information concerning the process of RNA editing. Editing can occur before splicing.
openaire   +2 more sources

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

Advanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang, Jingjing Fu, Jin Chai, Hongyu Jiang, Fan Chen, Yufei Zhang, Weihao Zhao, Xian Song, Zhihao Zhou, Lingtao Fang, Qiyao Huang, Peng Li, Zijian Zheng   +12 more
wiley   +1 more source

ORF138 causes abnormal lipid metabolism in the tapetum that leads to Ogu cytoplasmic male sterility in Brassica napus

Journal of Integrative Agriculture
Mutations and rearrangements of mitochondrial genes cause plant cytoplasmic male sterility. It is a significant way to utilize hybrid vigor to enhance crop yield.
Xiaoyu Ge, Junlin Chen, Ouqi Li, Min Zou, Baolong Tao, Lun Zhao, Jing Wen, Bin Yi, Jinxing Tu, Jinxiong Shen   +9 more
doaj   +1 more source

Gene, protein and network of male sterility in rice

Frontiers in Plant Science, 2013
Rice is one of the most important model crop plants whose heterosis has been well exploited in commercial hybrid seed production via a variety of types of male sterile lines. Hybrid rice cultivation area is steadily expanding around the world, especially
Wang eKun, Wang eKun, Peng eXiaojue, Ji eYanxiao, Pingfang eYang, Zhu eYingguo, Shaoqing eLi   +6 more
doaj   +1 more source