Results 21 to 30 of about 2,408 (165)

Giant Renal Cell Carcinoma Surgical Challenges and Life Expectancy: A Real-World Analysis of Serial Cases

open access: yesAsian Pacific Journal of Cancer Care, 2021
Giant renal cell carcinoma is a rare case. We reported six cases of giant renal cell carcinoma, which required surgical resection of the tumor, including a 9.900 cm3 of encapsulated neoplasm removal. To our knowledge, this is the largest giant clear cell
Sawkar Vijay Pramod   +3 more
doaj   +1 more source

Complete remission of renal cell carcinoma with lung carcinomatous lymphangiosis after primary therapy with immune checkpoint inhibitors followed by partial nephrectomy for surgical consolidation

open access: yesIJU Case Reports, 2022
Introduction Cytoreductive nephrectomy has been used in combination with systemic therapy for the treatment of metastatic renal cell carcinoma, although its efficacy in the era of immune checkpoint inhibitors remains controversial. Case presentation A 57‐
Takanari Kambe   +9 more
doaj   +1 more source

Role of cytoreductive nephrectomy in the targeted therapy era: A systematic review and meta-analysis [PDF]

open access: yesInvestigative and Clinical Urology, 2018
Purpose: To determine the effectiveness and harm of cytoreductive nephrectomy versus no intervention in patients with metastatic renal carcinoma who undergo targeted therapy to improve overall survival.
Herney A. García-Perdomo   +2 more
doaj   +1 more source

Cytoreductive nephrectomy in the age of immunotherapy-based combination treatment. [PDF]

open access: yesInvestig Clin Urol, 2023
Renal cell carcinoma (RCC) displays a wide spectrum of oncological prognosis and clinical behavior, and is noted for its generally poor outcome in metastatic settings. However, the introduction of immunotherapy after the cytokine era has changed the landscape of treatment for metastatic RCC, outperforming previous targeted therapy and providing new ...
Song SH, Lee S.
europepmc   +4 more sources

Impact of Cytoreductive Nephrectomy on Survival in Patients with Metastatic Renal Cell Carcinoma Treated by Targeted Therapy

open access: yesChinese Medical Journal, 2016
Background: The metastatic renal cell carcinoma (mRCC) patients treated with upfront cytoreductive nephrectomy combined with α-interferon yields additional overall survival (OS) benefits.
Yan Song   +12 more
doaj   +1 more source

A case of metastatic renal cell carcinoma successfully treated with deferred cytoreductive nephrectomy following lenvatinib plus pembrolizumab combination therapy

open access: yesIJU Case Reports, 2023
Introduction Combination therapy using immuno‐oncology drugs with tyrosine kinase inhibitors is increasingly important in the therapeutic strategy for metastatic renal cell carcinomas.
Hiroaki Sato   +9 more
doaj   +1 more source

Cytoreductive nephrectomy and its role in the present-day period of targeted therapy

open access: yesTherapeutic Advances in Urology, 2015
The beneficial effect of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma in the immunotherapy era was based on two prospective randomized trials.
Stephen H. Culp
doaj   +1 more source

Current role of cytoreductive nephrectomy in metastatic renal cell carcinoma

open access: yesUrology Research and Practice, 2021
Historically, immediate cytoreductive nephrectomy (CN) was considered the standard of care in patients with metastatic renal cell carcinoma (mRCC) who were fit enough to undergo surgery. Recently, 2 randomized controlled trials, SURTIME and CARMENA, have
Charles Van Praet   +9 more
doaj   +1 more source

Epidemiological and Histopathological Study of Renal Cell Carcinoma: A Retrospective Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Introduction: The incidence of Renal Cell Carcinomas (RCCs) has increased steadily and they have become the seventh most common histological type of cancer across the globe.
Amit Kumar   +3 more
doaj   +1 more source

Cytoreductive nephrectomy in metastatic renal cell carcinoma. [PDF]

open access: yesCochrane Database Syst Rev
Nephrectomy is the surgical removal of all or part of a kidney. When the aim of nephrectomy is to reduce tumor burden in people with established metastatic disease, the procedure is called cytoreductive nephrectomy (CN). CN is typically combined with systemic anticancer therapy (SACT).
Dahm P   +6 more
europepmc   +4 more sources

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