Results 31 to 40 of about 2,408 (165)

Spontaneous regression of multiple pulmonary metastases accompanied by normalization of serum immune markers following cytoreductive nephrectomy in a patient with clear‐cell renal cell carcinoma

IJU Case Reports, 2021
Introduction The spontaneous regression of metastases, which mostly occurs after surgical resection of the primary tumor, has been described in various malignancies, including renal cell carcinoma.
Akihito Okazaki, Toshiki Kijima, Philipp Schiller, Natsumi Ishikawa, Hirotaka Fuchizawa, Kohei Takei, Issei Suzuki, Kazumasa Sakamoto, Toyonori Tsuzuki, Takao Kamai   +9 more
doaj   +1 more source

The role of cytoreductive nephrectomy in renal cell carcinoma patients with liver metastasis

Biomolecules & Biomedicine, 2021
It is widely accepted that renal cell carcinoma (RCC) with liver metastasis (LM) carries a dismal prognosis. We aimed to explore the value of cytoreductive nephrectomy among these patients.
Boda Guo, Shengjing Liu, Miao Wang, Huimin Hou, Ming Liu   +4 more
doaj   +1 more source

Stereotactic body radiation therapy to the kidney for metastatic renal cell carcinoma: A narrative review of an emerging concept

Cancer Treatment and Research Communications, 2023
This narrative review provides a historical overview of cytoreductive nephrectomy for metastatic renal cell carcinoma (mRCC) and examines the safety and therapeutic potential of cytoreductive stereotactic body radiation therapy (SBRT) for mRCC in the ...
Claire Hao, Jason Liu, Colton Ladbury, Tanya Dorff, Sagus Sampath, Sumanta Pal, Savita Dandapani   +6 more
doaj   +1 more source

Efficacy of immunotherapy-based immediate cytoreductive nephrectomy vs. deferred cytoreductive nephrectomy in metastatic renal cell carcinoma.

European review for medical and pharmacological sciences, 2023
This study was performed to evaluate the efficacy of immediate cytoreductive nephrectomy (CRN) followed by programmed cell death factor-1 (PD-1) inhibitors vs. deferred CRN after the administration of 4 cycles of neoadjuvant therapy using nivolumab preceding the debulking and postoperative chemotherapy in metastatic renal cell carcinoma (mRCC).We ...
Shen, X.-P., Xie, M., Wang, J.-S., Guo, X.   +3 more
openaire   +2 more sources

Trends in the Use of Cytoreductive Nephrectomy in the United States [PDF]

Clinical Genitourinary Cancer, 2012
Two randomized trials published in 2001 established CyNx for patients with metastatic renal carcinoma (mRCC) as a treatment standard in the cytokine era. However, first-line systemic therapy for mRCC changed in 2005 with FDA approval of VEGFR TKIs. We evaluated the patterns of use of CyNx from 2000 to 2008.The National Cancer Database was queried for ...
Che-Kai, Tsao, Alexander C, Small, Erin L, Moshier, Benjamin A, Gartrell, Juan P, Wisnivesky, Guru, Sonpavde, James H, Godbold, Michael A, Palese, Simon J, Hall, William K, Oh, Matthew D, Galsky   +10 more
openaire   +2 more sources

Progression‐free survival and objective response rate as a surrogate end point for overall survival in metastatic renal cell carcinoma: A systematic review and meta‐analysis

Cancer, Volume 132, Issue 19, 1 October 2026.
ABSTRACT The objective of this systematic review and meta‐analysis was to evaluate the validity of progression‐free survival (PFS) and the objective response rate (ORR) as surrogate end points for overall survival (OS) in randomized controlled trials (RCTs) of metastatic renal cell carcinoma.
Russell Leong, David Chen, Laith Almasri, Nicholas Lum, Karren Xiao, Maryam Soleimani, Christian K. Kollmannsberger, Srinivas Raman   +7 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of Perioperative Muscle Wasting Following Major Abdominal Surgery

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Muscle wasting in the perioperative period is a frequent and clinically significant complication following major abdominal surgery and is associated with adverse outcomes, including increased postoperative complications, prolonged hospitalisation and worsened mortality.
A. Reynolds, N. M. George, A. Papadopoulou, B. Creagh‐Brown   +3 more
wiley   +1 more source

An evaluation of the role of tumor load in cytoreductive nephrectomy

Canadian Urological Association Journal, 2020
Introduction: New radiological tools can accurately provide preoperative three-dimensional spatial assessment of metastatic renal cell carcinoma (RCC) We aimed to determine whether the distribution, volume, shape, and fraction of RCC resected in a cytoreductive nephrectomy associates with survival. Methods: We retrospectively reviewed 560 ...
Andrew W, Silagy, Cihan, Duzgol, Julian, Marcon, Renzo G, DiNatale, Roy, Mano, Kyle A, Blum, Ed, Reznik, Martin H, Voss, Robert J, Motzer, Jonathan A, Coleman, Paul, Russo, Oguz, Akin, A Ari, Hakimi   +12 more
openaire   +3 more sources

Is Cytoreductive Nephrectomy Still a Standard of Care in Metastatic Renal Cell Carcinoma?

Journal of Kidney Cancer and VHL, 2019
Cytoreductive nephrectomy has been an integral part of management in metastatic renal cell carcinoma for patients with good performance status, based on the benefit shown by prospective trials in the interferon era and retrospective trials in the ...
Alex Renner, Suraj Rajesh Samtani, Arnaldo Marín, Mauricio Burotto   +3 more
doaj   +1 more source

Oligoprogressive renal cell carcinoma: What is the role of surgery?

BJU International, Volume 138, Issue 2, Page 219-228, August 2026.
Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re, William H.J. Ince, Leo Bickley, James P. Blackmur, Mouhamad H. Ismail, Justicia Kyeremeh, Teele Kuusk, Eva Mendes Serrao, James O. Jones, Grant D. Stewart   +9 more
wiley   +1 more source