Results 61 to 70 of about 2,590,210 (272)

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

Med Research, EarlyView.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu, Aihetaimujiang Anwaier, Qintao Ge, Siqi Zhou, Xi Tian, Shuxuan Zhu, Guohai Shi, Yu Zhu, Dingwei Ye, Mierxiati Abudurexiti, Hailiang Zhang   +10 more
wiley   +1 more source

Comparison of ultrasound with computed tomography and whole‐body diffusion‐weighted MRI in prediction of surgical outcome using ESMO‐ESGO criteria in patients with tubo‐ovarian carcinoma: prospective ISAAC study

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To test the non‐inferiority of extended abdominopelvic ultrasound examination compared with contrast‐enhanced computed tomography (CT) and whole‐body diffusion‐weighted magnetic resonance imaging (WB‐DWI/MRI) in discriminating preoperatively between resectable and non‐resectable disease based on the European Society for Medical ...
D. Fischerova, P. Pinto, J. L. Alcázar Zambrano, J. Vara‐Garcia, V. Chiappa, F. Raspagliesi, D. Franchi, A. V. Urbinati, A. C. Testa, J. Jarkovsky, D. Cibula, F. Moro, Collaborators, F. Frühauf, J. Slama, R. Kocian, S. Alessi, G. Avesani, K. Benesova, A. Burgetova, G. Calareso, L. Lambert, M. Masek, A. Fagotti, C. Panico, P. Pricolo, R. Vigorito   +26 more
wiley   +1 more source

Advanced low grade serous ovarian cancer: A retrospective analysis of surgical and chemotherapeutic management in two high volume oncological centers

Frontiers in Oncology, 2022
Simple summaryLow-grade serous ovarian cancer (LGSOC) represents an uncommon histotype of serous ovarian cancer (accounting for approximately 5% of all ovarian cancer) with a distinct behavior compared to its high-grade serous counterpart, characterized ...
Paolo Di Lorenzo, Paolo Di Lorenzo, Vincenza Conteduca, Vincenza Conteduca, Emanuela Scarpi, Marco Adorni, Francesco Multinu, Annalisa Garbi, Ilaria Betella, Tommaso Grassi, Tommaso Bianchi, Giampaolo Di Martino, Andrea Amadori, Paolo Maniglio, Isabella Strada, Silvestro Carinelli, Marta Jaconi, Giovanni Aletti, Giovanni Aletti, Vanna Zanagnolo, Angelo Maggioni, Luca Savelli, Ugo De Giorgi, Fabio Landoni, Nicoletta Colombo, Nicoletta Colombo, Robert Fruscio, Robert Fruscio   +27 more
doaj   +1 more source

A Cost Consequence Analysis of Seven Diagnostic Strategies for Ovarian Cancer: A Model‐Based Economic Evaluation

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess the costs and consequences of seven diagnostic strategies for ovarian cancer in pre‐ and post‐menopausal women with symptoms in secondary care. Design Economic evaluation alongside a prospective single‐arm diagnostic accuracy study.
Samuel J. Perry, Donal Griffin, Eleanor V. Williams, Tracy E. Roberts, Fong Lien Kwong, Sarah Williams, Jon Deeks, Katie Scandrett, Ridhi Agarwal, Sudha S. Sundar, Mark Monahan   +10 more
wiley   +1 more source

Colorectal cancer with synchronous distant metastases: rationale for cytoreductive surgery and its perspectives – a surgeons view

Тазовая хирургия и онкология, 2015
A rationale for cytoreductive surgery in colorectal cancer patients with multiple liver metastases is discussed in the article. Not only does it improve their quality of life and prevent life-threatening complications, but also facilitates further ...
V. A. Aliyev, Yu. A. Barsukov, A. V. Nikolayev, R. I. Tamrazov, Z. Z. Mamedli, A. O. Atroshchenko, D. V. Kuzmichev   +6 more
doaj   +1 more source

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parralel-group, phase II-III, randomised, superiority study (CAIRO6)

BMC Cancer, 2019
Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands.
K. Rovers, C. Bakkers, G. Simkens, J. Burger, S. Nienhuijs, G. Creemers, A. M. Thijs, A. Brandt-Kerkhof, E. Madsen, N. Ayez, N. L. de Boer, E. van Meerten, J. Tuynman, M. Kusters, N. Sluiter, H. Verheul, H. J. van der Vliet, M. Wiezer, D. Boerma, E. Wassenaar, M. Los, C. B. Hunting, A. Aalbers, N. Kok, K. Kuhlmann, H. Boot, M. Chalabi, S. Kruijff, L. Been, R. V. van Ginkel, D. D. de Groot, R. Fehrmann, J. D. de Wilt, A. Bremers, P. D. de Reuver, S. Radema, K. Herbschleb, W. V. van Grevenstein, A. Witkamp, M. Koopman, N. Haj Mohammad, E. V. van Duyn, W. Mastboom, L. Mekenkamp, J. Nederend, M. Lahaye, P. Snaebjornsson, C. Verhoef, H. V. van Laarhoven, A. Zwinderman, J. Bouma, O. Kranenburg, I. van ’t Erve, R. Fijneman, M. Dijkgraaf, P. Hemmer, C. Punt, P. Tanis, I. D. de Hingh   +58 more
semanticscholar   +1 more source

Comparative Outcomes of Reinforced Tension‐Line Sutures Versus Standard Closure Techniques in Patients Undergoing Laparotomy: A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The reinforced tension‐line suture (RTLS) technique distributes mechanical stress more evenly than traditional closure when closing a laparotomy wound, potentially reducing incisional hernia (IH) risk. We aimed to compare outcomes of RTLS versus standard closure techniques in patients undergoing laparotomy. Methods Systematic search
Rama H. G. Mikhail, Shahin Hajibandeh, Shahab Hajibandeh, Marty Smith, Ee Jun Ban, Rodney Jacobs, Siobhan C. McKay   +6 more
wiley   +1 more source

Systematic Pelvic and Paraaortic Lymph Node Dissection in Advanced Ovarian Cancer—Technical Aspects and Current Evidence-Based Data for Clinical Decision-Making

Surgical Techniques Development
Cytoreductive surgery in the context of a multidisciplinary approach, including adjuvant and neoadjuvant therapy (when indicated), aims ideally to obtain complete resection and represents the cornerstone for long-term survival in patients with advanced ...
Traian Dumitrascu
doaj   +1 more source

Colorectal cancer with synchronous lung metastases: clinical characteristics, treatment, prognosis

Тазовая хирургия и онкология, 2016
Objective: to evaluate the impact of cytoreductive surgery on treatment results in patients with colorectal cancer and synchronous lung metastases.Materials and methods.
A. O. Rasulov, M. M. Davydov, V. A. Aliev, S. S. Gordeev, A. K. Allakhverdiev, B. B. Akhmedov, A. V. Nalbandyan   +6 more
doaj   +1 more source

Concurrent hysterectomy and bilateral salpingo-oophorectomy during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for non-gynecologic cancers

Gynecologic Oncology Reports, 2020
Hyperthermic intraperitoneal chemotherapy (HIPEC) is a key component of treatment in non-gynecologic peritoneal surface malignancies. As many as 10–15% of patients with a gastrointestinal primary malignancy will present with carcinomatosis.
McKayla J. Riggs, Miranda Lin, Joseph Kim, Prakash Pandalai, Charles S. Dietrich, III   +4 more
doaj   +1 more source