Results 81 to 90 of about 2,906,691 (234)

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, Volume 13, Issue 19, 2 April 2026.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

Comparison of two cardiac output monitors, qCO and LiDCO, during general anesthesia [PDF]

, 2016
Background: Optimization of cardiac output (CO) has been evidenced to reduce postoperative complications and to expedite the recovery. Likewise, CO and other dynamic cardiac parameters can describe the systemic blood flow and tissue oxygenation state and
Escrivá, Jesús, Fort, Pol, Gabarrón, Eva, Liao, Q, Pan, Y., Shengjin, Ge, Vallverdú Ferrer, Montserrat   +6 more
core   +1 more source

Ultra-radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer [PDF]

, 2011
BACKGROUND: Ovarian cancer is the sixth most common cancer among women and the leading cause of death in women with gynaecological malignancies. Opinions differ regarding the role of ultra-radical (extensive) cytoreductive surgery in ovarian cancer ...
Ang, C, Bryant, A, Chan, KKL, Dickinson, HO, Naik, R   +4 more
core   +1 more source

Combining Small‐Molecular Compounds With CAR T‐Cell Therapy: Novel Strategies for Enhanced Cancer Immunotherapy

Cancer Innovation, Volume 5, Issue 2, April 2026.
Chimeric antigen receptor (CAR) T‐cell therapy, although revolutionary for haematological malignancies, faces significant challenges, including T‐cell exhaustion, limited persistence, and treatment‐related toxicity. The integration of small‐molecule compounds offers a promising strategy to overcome these limitations.
Rangzi Yi, Zijian Zhang, Yang Yang, Haichuan Zhu   +3 more
wiley   +1 more source

Early experience with targeted therapy and dendritic cell vaccine in metastatic renal cell carcinoma after nephrectomy [PDF]

, 2011
PURPOSE: Metastatic renal cell carcinoma (RCC) is one of the most treatment-resistant malignancies and nephrectomy, isolated or combined with systemic chemotherapy typically has limited or no effectiveness.
CRIPPA, Alexandre, DALL'OGLIO, Marcos F., LEITE, Katia R. M., REIS, Sabrina T. dos, SOUSA-CANAVEZ, Juliana M., Srougi, Miguel, TANNO, Fabio Y., TISEO, Bruno C.   +7 more
core   +2 more sources

Society of Onco-Anaesthesia and Perioperative Care consensus guidelines for perioperative management of patients for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC)

Indian Journal of Anaesthesia, 2019
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) for primary peritoneal malignancies or peritoneal spread of malignant neoplasm is being done at many centres worldwide.
S. Solanki, S. Mukherjee, V. Agarwal, R. Thota, Kalpana Balakrishnan, S. Shah, Neha Desai, R. Garg, R. Ambulkar, Nitin Bhorkar, Viplab Patro, S. Sinukumar, Meenakshi V Venketeswaran, M. Joshi, R. H. Chikkalingegowda, V. Gottumukkala, P. Owusu-Agyemang, A. Saklani, S. Mehta, R. Seshadri, J. Bell, S. Bhatnagar, J. Divatia   +22 more
semanticscholar   +1 more source

Efficacy and Safety of Multivisceral Resection for Ovarian Cancer: A Comparative Study of Gynecologic Oncologists and Multidisciplinary Surgeons

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Background Advanced ovarian cancer often presents with extensive pelvic and abdominal metastases, even malignant pleural effusion. Consequently, multivisceral resection has become the common surgical approach to achieve optimal resection of ovarian cancer.
Luxin Ye, Qi Xue, Xianzhong Cheng, Ping Liu, Qian Zhao, Jiahui Chen, Xuening Wang, Yourong Chen, Xia Xu, Wenwen Guo, Jing Ni, Xiaoxiang Chen   +11 more
wiley   +1 more source

Epigenetic Compound Library Screen Identifies Ibrutinib as an Inhibitor of Ovarian Clear Cell Carcinoma Viability

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Background Ovarian clear cell carcinoma (OCCC) is an endometriosis‐associated ovarian cancer subtype. Somatic mutations in OCCC are reported in ARID1A, PIK3CA, and the TERT promoter (TERTp), as well as less commonly in KRAS and TP53 among other genes. OCCC is typically resistant to standard‐of‐care chemotherapy, especially after relapse. While
Yue Ma, Kristie‐Ann Dickson, Farhana A. Sarker, Amani Alghalayini, Natisha R. Field, Tao Xie, Tali S. Skipper, Anastasia Karafotias, Sarina Briscas, Christine Yee, Caroline E. Ford, Nikola A. Bowden, Nham Tran, Deborah J. Marsh   +13 more
wiley   +1 more source

Systemic treatment of patients with metachronous peritoneal carcinomatosis of colorectal origin [PDF]

, 2015
Combining chemotherapy and targeted therapies has resulted in an enhanced survival in metastatic colorectal cancer (mCRC) patients. However, the result of this palliative treatment in patients with metachronous peritoneal carcinomatosis (PC) remains ...
Creemers, G.J.M. (Geert-Jan), Gestel, Y.R.B.M. (Yvette) van, Hingh, I.H.J.T. (Ignace) de, Lemmens, V.E.P.P. (Valery), Oudheusden, T.R. (Thijs) van, Razenberg, L.G.E.M. (Lieke)   +5 more
core   +3 more sources

Interval debulking surgery is not worth the wait: a National Cancer Database study comparing primary cytoreductive surgery versus neoadjuvant chemotherapy

International Journal of Gynecological Cancer, 2019
Objective In previous studies, neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary cytoreductive surgery as initial treatment for advanced epithelial ovarian cancer. Our study aimed to compare surgical and survival
Y. Lyons, H. Reyes, M. Mcdonald, A. Newtson, E. Devor, D. Bender, M. Goodheart, J. Gonzalez Bosquet   +7 more
semanticscholar   +1 more source