Results 101 to 110 of about 1,471,694 (149)

Prognostic factors and oncologic outcome in 146 patients with colorectal peritoneal carcinomatosis treated with cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: Italian multicenter study S.I.T.I.L.O.

, 2011
International audienceThe present study was specifically designed to assess the major clinical and pathological variables of patients with colorectal peritoneal carcinomatosis in order to investigate whether currently used criteria appropriately select ...
Virzì, S., Rossi, C.R., C.R. Rossi, M. La Pinta, M. Valle, de Simone, M., Garofalo, A., La Pinta, M., M. De Simone, M. Vaira, Vaira, M., I. Monsellato, Deraco, M., Cavaliere, F., Monsellato, I., M. Deraco, P. Pilati, Pilati, P., P. Perri, F. Di Filippo, F. Guadagni, Perri, P., S. Virzì, F. Cavaliere, Giannarelli, D., Valle, M., Guadagni, F., D. Giannarelli, Di Filippo, F., A. Garofalo   +29 more
core   +1 more source

Prospective longitudinal study of quality of life following cytoreductive surgery and intraperitoneal chemotherapy for pseudomyxoma peritonei [PDF]

, 2010
International audiencePseudomyxoma peritonei (PMP) is characterized by mucinous ascites, predominantly arising form a perforated tumour of the appendix. This study aimed to assess health related quality of life (HRQL) in patients following cytoreductive ...
B.J. Moran, Moran, Brendan J., H. Youssef, Yadegarfar, Ghasem, Alves, Suzanne, S. Alves, G. Yadegarfar, Youssef, Haney, Mohamed, Faheez, F. Mohamed   +9 more
core   +1 more source

Progression‐free survival and objective response rate as a surrogate end point for overall survival in metastatic renal cell carcinoma: A systematic review and meta‐analysis

Cancer, Volume 132, Issue 19, 1 October 2026.
ABSTRACT The objective of this systematic review and meta‐analysis was to evaluate the validity of progression‐free survival (PFS) and the objective response rate (ORR) as surrogate end points for overall survival (OS) in randomized controlled trials (RCTs) of metastatic renal cell carcinoma.
Russell Leong, David Chen, Laith Almasri, Nicholas Lum, Karren Xiao, Maryam Soleimani, Christian K. Kollmannsberger, Srinivas Raman   +7 more
wiley   +1 more source

Ovarian cancer during pregnancy: Pregnancy‐adjusted inflammatory and haematologic signatures for earlier risk recognition and clinical decision‐making

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Pregnancy alters haematologic and inflammatory profiles, potentially masking ovarian cancer. Integrating trimester‐specific NLR, PLR, SII, CRP, CA‐125, haemoglobin, platelet dynamics, and imaging may improve risk stratification. Multimodal biomarkers, longitudinal monitoring, and multidisciplinary assessment can support earlier detection and ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Surface Malignancies: Learning Curve Based on Surgical and Oncological Outcomes

, 2020
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a complex, highly specialized procedure used to treat peritoneal surface malignancies (PSM) [...
Wojciech P. Polkowski, Jerzy Mielko, Karol Rawicz-Pruszyński, Katarzyna Sędłak, Katarzyna Gęca, Magdalena Kwietniewska   +5 more
core   +1 more source

The German ONKOPEDIA Guideline for Myelofibrosis in 2025—Recommendations of an MPN Expert Panel of the German Society for Hematology and Oncology (DGHO)

International Journal of Cancer, Volume 159, Issue 7, Page 1633-1641, 1 October 2026.
ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Martin Griesshammer, Haifa Kathrin Al‐Ali, Gabriela M. Baerlocher, Konstanze Döhner, Steffen Koschmieder, Nicolaus Kröger, Petro E. Petrides, Dominik Wolf, Florian H. Heidel   +8 more
wiley   +1 more source

α2,3‐Sialyltransferase (ST3Gal1) regulates endometrioid‐type epithelial ovarian cancer cell migration and invasion via VEGF‐R2/JAK2/STAT3 signaling cascades

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 453-465, October 2026.
Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao, Chia‐Hao Liu, Szu‐Ting Yang, Chen‐Hao Lin, Liang‐Wei Wang, Peng‐Hui Wang   +5 more
wiley   +1 more source

Impact of second look laparotomy and secondary cytoreductive surgery at second-look laparotomy in ovarian cancer patients

, 2001
Objective. Currently, no prospective study supports or refutes the value of secondary cytoreductive surgery in patients with ovarian cancer. We therefore reviewed the surgical data of patients who underwent second-look laparotomy (SLL) with or without ...
Sevelda, P, Obermair, A
core   +1 more source

A Systematic Review and Meta‐Analysis of Perioperative Muscle Wasting Following Major Abdominal Surgery

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Muscle wasting in the perioperative period is a frequent and clinically significant complication following major abdominal surgery and is associated with adverse outcomes, including increased postoperative complications, prolonged hospitalisation and worsened mortality.
A. Reynolds, N. M. George, A. Papadopoulou, B. Creagh‐Brown   +3 more
wiley   +1 more source

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source