Results 61 to 70 of about 17,965 (195)

Effects of short‐course preoperative endocrine therapy on tumour morphology and immunohistochemical profile in oestrogen receptor‐positive, HER2‐negative breast cancer

Histopathology, EarlyView.
Short‐course preoperative endocrine therapy induces histopathological and immunophenotypic changes in oestrogen receptor‐positive, HER2‐negative breast cancer. Proliferative response is independently associated with baseline genomic risk (MammaPrint) and progesterone receptor expression.
Claudia Grosse, Alexandra Grosse, Petar Noack, Caroline Ines Preuss, Heike Kathleen Schwarz, Bruno Schneeweiss, Thomas Gitter, Peter Schrenk, Rupert Langer   +8 more
wiley   +1 more source

A proposal of Brazilian Society of Surgical Oncology for standardizing cytoreductive surgery plus hypertermic intraperitoneal chemotherapy procedures in Brazil: pseudomixoma peritonei, appendiceal tumors and malignant peritoneal mesothelioma

Revista do Colégio Brasileiro de Cirurgiões
Cytoreductive surgery plus hypertermic intraperitoneal chemotherapy has emerged as a major comprehensive treatment of peritoneal malignancies and is currently the standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome ...
Thales Paulo Batista, Bruno José Queiroz Sarmento, Janina Ferreira Loureiro, Andrea Petruzziello, Ademar Lopes, Cassio Cortez Santos, Cláudio de Almeida Quadros, Eduardo Hiroshi Akaishi, Eduardo Zanella Cordeiro, Felipe José Fernández Coimbra, Gustavo Andreazza Laporte, Leonaldson Santos Castro, Ranyell Matheus Spencer Sobreira Batista, Samuel Aguiar Júnior, Wilson Luiz Costa Júnior, Fábio Oliveira Ferreira   +15 more
doaj   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

Impact of postoperative infection on changes in leucocyte levels in early postoperative period in patients undergoing splenectomy during cytoreductive surgery for gynaecological malignancy

BMC Cancer
Background In cytoreductive surgery for gynecological cancers, 13-25% of patients require splenectomy. Therefore, hematological parameters change in the post-splenectomy period, especially leucocytosis and thrombocytosis.
Yeşim Özkaya Uçar, Tufan Arslanca, Okan Aytekin, Gülşah Tiryaki Güner, Serpil Ünlü, Günsu Kimyon Cömert, Fatih Kılıç, Aziz Ahmet Sürel, Taner Turan   +8 more
doaj   +1 more source

Implementation of enhanced recovery protocols in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for metastatic ovarian cancer following neoadjuvant chemotherapy. A feasibility study

Gynecologic Oncology Reports
Objective: The aim of this study is to evaluate the implementation of the elements of enhanced recovery (ERAS) protocols in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for metastatic ovarian cancer ...
Anastasios Pandraklakis, Chrysoula Liakou, MariaClelia La Russa, Rocio Ochoa-Ferraro, Adam Stearns, Nikolaos Burbos   +5 more
doaj   +1 more source

Complex Genetic Architecture in RASopathies: Constitutional PTPN11 and Mosaic RIT1 Pathogenic Variants Underlying Severe Noonan Syndrome With Adult‐Onset Acute Myeloid Leukemia

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1879-1883, August 2026.
ABSTRACT Noonan syndrome (NS) is a genetically heterogeneous disorder characterized by a broad spectrum of clinical features resulting from dysregulation of the RAS/MAPK pathway. Although complex genotypes are increasingly recognized in NS, cases harboring two distinct pathogenic variants in different NS genes remain extremely rare.
Francesco Prevedello, Dario Seif Ali, Chiara Piccolo, Chiara Rigon, Monica Forzan, Elena Tacchetto, Roberta Palmitessa, Davide Calosci, Leonardo Salviati, Carmela Gurrieri, Eva Trevisson   +10 more
wiley   +1 more source

Survival Outcomes and Prognostic Factors in Patients With Primary Central Nervous System Low‐Grade B‐Cell Lymphoma: A Population‐Based Cohort Study

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT The incidence of primary central nervous system low‐grade B‐cell lymphoma (PCNSL‐LG) is rare. We aimed to provide the first large‐scale analysis of treatment modalities, survival trends, and prognostic factors for PCNSL‐LG. Patient data diagnosed between 2000 and 2021 were extracted from the Surveillance, Epidemiology, and End Results (SEER ...
Lvwen Chen, Lei Cao, Yuxiao Zhao, Hailing Liu, Sanmei Wang, Miao Zhong, Xiran Wang, Jing Zhang, Xiaoyan Qu, Zhengxu Sun, Lei Fan, Ran Li   +11 more
wiley   +1 more source

Oligoprogressive renal cell carcinoma: What is the role of surgery?

BJU International, Volume 138, Issue 2, Page 219-228, August 2026.
Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re, William H.J. Ince, Leo Bickley, James P. Blackmur, Mouhamad H. Ismail, Justicia Kyeremeh, Teele Kuusk, Eva Mendes Serrao, James O. Jones, Grant D. Stewart   +9 more
wiley   +1 more source

Sustained disease control in ovarian carcinosarcoma treated with postoperative hyperthermic intraperitoneal chemotherapy and targeted maintenance: a case report

Frontiers in Medicine
ObjectiveOvarian carcinosarcoma (OCS) is a rare and highly aggressive malignancy with no established standard treatment and a poor prognosis. This case describes sustained disease control achieved through the combination of cytoreductive surgery followed
Shuo Xu, Xinjun Li, Xiangnan Zhang, Ren Xu, Lu Sang, Yanan Ren, Ning Sun, Xiao Shao, Shengpu Wang   +8 more
doaj   +1 more source

Patient Expectations in High‐Risk Abdominal Surgery for Cancer

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Background Despite the central role of expectations in informed consent and surgical shared decision‐making, patient expectations frequently remain unelicited or underexplored and are often assumed rather than explicitly addressed. Objective To explore how patients form expectations about high‐risk abdominal surgery for cancer and how ...
Kimberly E. Kopecky, Jacquelyn E. F. Speer, Janet Julson, Alizeh Abbas, Olivia Monton, Fabian M. Johnston, J. Nicholas Odom   +6 more
wiley   +1 more source