Susceptibility to the health effects of DNA damage depends on a person's ability to repair DNA damage, but DNA repair has been difficult to measure in populations. A functional assay called FM‐HCR is used to measure DNA repair in 6 major pathways across 56 individuals.
Ting Zhai+7 more
wiley +1 more source
Remission induction with cytosine arabinoside and L-Asparaginase in acute lymphoblastic leukaemia [PDF]
T J McElwain, R. M. Hardisty
openalex +1 more source
Magnetic Soft Robots for Targeted Bacterial Delivery and Enhanced Tumor Spheroid Disaggregation
Magnetic soft robots encapsulating probiotic bacteria offer a new strategy for targeted cancer therapy. These millimeter‐scale hydrogel robots enable magnetically guided delivery, controlled bacterial release, and enhanced tumor spheroid disintegration.
Tamara Krauss+5 more
wiley +1 more source
Cytogenetic and Morphologic Abnormalities in Human Bone Marrow Cells during Cytosine Arabinoside Therapy [PDF]
William R. Bell+4 more
openalex +1 more source
Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich+20 more
wiley +1 more source
Behavioral and biochemical effects of intracranial injection of cytosine arabinoside in goldfish. [PDF]
Luigi Casola+3 more
openalex +1 more source
Gene up-regulation by DNA demethylation in 35S-gshI-transgenic poplars (Populus x canescens) [PDF]
Gene expression levels of transgene 35S-gshI (γ-glutamylcysteine synthetase) cloned from E. coli, and the endogenous gene gsh1 of poplar (Populus x canescens) were upregulated by the DNA demethylating agent DHAC (5,6-dihydro-5'-azacytidine ...
Bittsánszky, András+7 more
core
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap+37 more
wiley +1 more source
The Production of Tolerance to Human Erythrocytes in the Rat with Cytosine Arabinoside or Cyclophosphamide [PDF]
Robert O. Gordon+2 more
openalex +1 more source
Nucleic Acid‐Based Molecular Machines for Biological Applications
Molecular machines are devices assembled from molecules with specific functions. In this review, the development of DNA nanostructures, which are then assembled into molecular machines, is summarized. Their classification and biological applications, such as biosensing, targeted therapy, and molecular circuits are introduced.
Yirong Guo, Xiaolei Zuo, Fangfei Yin
wiley +1 more source