ABSTRACT Rapid phenotypic change may be mediated by intergenerational transmission of early developmental experiences. In birds, exposure to glucocorticoids during early development can alter global DNA methylation and gene expression. However, DNA methylation is labile, and it is currently unclear whether the impacts of stress suffered during juvenile
Anna Miltiadous +5 more
wiley +1 more source
Case Report: Juvenile dermatomyositis complicated by acute myeloid leukemia: achievement of sustained remission through hematopoietic stem cell transplantation. [PDF]
Fu P +8 more
europepmc +1 more source
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy +7 more
wiley +1 more source
Sequence context and methylation interact to shape germline mutation rate variation at CpG sites. [PDF]
Chandra S, Gao Z.
europepmc +1 more source
Abstract Objectives Exclusive enteral nutrition (EEN) is the first‐line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the anti‐inflammatory effects of EEN, studying the nutritional composition and transforming growth factor‐β (TGF‐β) effects, in ...
Kawthar Boumessid +6 more
wiley +1 more source
Design, Synthesis, and Evaluation of a Novel Phenanthrene Derivative as a Potential DNA Intercalator. [PDF]
Bouz G +10 more
europepmc +1 more source
Genetic sequencing of children with malrotation and midgut volvulus: A cross‐sectional study
Abstract Objectives Intestinal malrotation with midgut volvulus can cause a particularly severe form of pediatric intestinal failure and is often a cause of ultra‐short bowel syndrome (SBS), with longer dependence on parenteral nutrition. While malrotation can be found in several genetic syndromes, most occurrences of this condition are not associated ...
Jonathan A. Salazar +9 more
wiley +1 more source
Is It Possible to Trap 4HNE, the Main Degradation Product of Omega-6? A Theoretical Study of Potential Scavengers. [PDF]
Ramírez R, Martínez A.
europepmc +1 more source
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira +3 more
wiley +1 more source
Electron transfer properties of biobased and biodegradable polymers: PHA as a case study. [PDF]
Perez-Sanchez E +2 more
europepmc +1 more source

