Results 161 to 170 of about 555,685 (380)

The cytoskeleton in Chediak-Higashi syndrome fibroblasts [PDF]

open access: bronze, 1980
RE Jr Ostlund   +4 more
openalex   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim   +10 more
wiley   +1 more source

Amoeboid cells undergo durotaxis with soft end polarized NMIIA

open access: yeseLife
Cell migration towards stiff substrates has been coined as durotaxis and implicated in development, wound healing, and cancer, where complex interplays between immune and non-immune cells are present.
Chenlu Kang   +8 more
doaj   +1 more source

Cytoskeleton organization is aberrantly rearranged in the cells of B chronic lymphocytic leukemia and hairy cell leukemia [PDF]

open access: bronze, 1986
F Caligaris-Cappio   +5 more
openalex   +1 more source

A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico   +8 more
wiley   +1 more source

NPFs-mediated actin cytoskeleton: a new viewpoint on autophagy regulation

open access: yesCell Communication and Signaling
Macroautophagy/autophagy is a lysosome-dependent catabolic process induced by various cellular stress conditions, maintaining the homeostasis of cells, tissues and organs.
Yuan Dong, Chengshi Quan
doaj   +1 more source

MAP2 phosphorylation: mechanisms, functional consequences, and emerging insights

open access: yesFrontiers in Cellular Neuroscience
Microtubule-associated protein 2 (MAP2) is a key regulator of cytoskeletal dynamics and neuronal function. It stabilizes microtubules, shapes dendrites, influences synaptic plasticity, and regulates transportation and protein synthesis through its ...
Jiali Lyu   +7 more
doaj   +1 more source

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

open access: yesAdvanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy