Results 171 to 180 of about 560,464 (384)

Kinetic regulation of kinesin’s two motor domains coordinates its stepping along microtubules

eLife
The two identical motor domains (heads) of dimeric kinesin-1 move in a hand-over-hand process along a microtubule, coordinating their ATPase cycles such that each ATP hydrolysis is tightly coupled to a step and enabling the motor to take many steps ...
Yamato Niitani, Kohei Matsuzaki, Erik Jonsson, Ronald D Vale, Michio Tomishige   +4 more
doaj   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

β-catenin-α-catenin and actomyosin signaling differentially regulate growth cone contours and axon undulation and branching of retinal ganglion cells in situ

Frontiers in Cellular Neuroscience
IntroductionCadherin adhesive and actomyosin signaling are key cytomechanical cues required for neuronal circuit formation, but whether they function together to sculpt developing neurons is not known. Previously, we demonstrated that a β-catenin mutant (
Valerie Lew, Sukaynah Khetani, Simran Kaur, William Woodward, Sukmin Sandhu, Radhika Rawat, Tamira Elul   +6 more
doaj   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Synergy between zinc and phorbol ester in translocation of protein kinase C to cytoskeleton [PDF]

, 1990
Peter D. Zalewski, Ian J. Forbes, C. Giannakis, Prue Cowled, W H Betts   +4 more
openalex   +1 more source

Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Current Biology, 2004
Dos D. Sarbassov, Siraj M. Ali, Do-Hyung Kim, D. Guertin, R. Latek, H. Erdjument‐Bromage, P. Tempst, D. Sabatini   +7 more
semanticscholar   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

EFP1 is an ER stress-induced glycoprotein which interacts with the pro-apoptotic protein Par-4 [PDF]

, 2009
We have isolated the rat ortholog of EFP1 (EF-hand binding protein 1) as a novel interaction partner of the pro-apoptotic protein Par-4 (prostate apoptosis response-4).
Appel, Sarah, Boosen, Meike, Koplin, Ansgar, Maertens, Barbara, Preuss, Ute, Vetterkind, Susanne   +5 more
core   +1 more source

Differential Involvement of the Actin Cytoskeleton in Differentiation and Mitogenesis of Thyroid Cells: Inactivation of Rho Proteins Contributes to Cyclic Adenosine Monophosphate-Dependent Gene Expression but Prevents Mitogenesis [PDF]

, 2005
Nathalie Fortemaison, Sara Blancquaert, Jacques E. Dumont, Carine Maenhaut, Klaus Aktories, Pierre P. Roger, Sarah Dremier   +6 more
openalex   +1 more source

Cell mechanics and the cytoskeleton

Nature, 2010
Daniel A. Fletcher, Daniel A. Fletcher, R. Mullins   +2 more
semanticscholar   +1 more source