Results 181 to 190 of about 489,558 (321)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

open access: yesAdvanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam   +5 more
wiley   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

open access: yesAdvanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang   +13 more
wiley   +1 more source

AtSEC22 Regulates Cell Morphogenesis via Affecting Cytoskeleton Organization and Stabilities

open access: gold, 2021
Guan Li   +14 more
openalex   +1 more source

Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells

open access: yesAdvanced Materials, EarlyView.
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park   +13 more
wiley   +1 more source

Peptide‐Induced Ferroelectricity in Charge‐Transfer Supramolecular Materials

open access: yesAdvanced Materials, EarlyView.
Bio‐inspired supramolecular charge‐transfer amphiphiles self‐assemble into nanoribbons in water, where peptide chirality‐induced symmetry breaking generates robust ferroelectricity across multiple systems. These water‐processable organic ferroelectrics also enhance neuronal outgrowth and electrophysiological maturity, offering a versatile strategy for ...
James V. Passarelli   +15 more
wiley   +1 more source

Polyphenols from <i>Inula oculus-christi</i> L. Induced Cell-Specific Membrane and Cytoskeleton Reorganization. [PDF]

open access: yesMembranes (Basel)
Veleva R   +9 more
europepmc   +1 more source

TMEM16A Maintains Acrosomal Integrity Through ERK1/2, RhoA, and Actin Cytoskeleton During Capacitation [PDF]

open access: gold
Ana L. Roa‐Espitia   +5 more
openalex   +1 more source

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