Results 301 to 310 of about 555,685 (380)

Mechanical stability of the cell nucleus – roles played by the cytoskeleton in nuclear deformation and strain recovery

Journal of Cell Science, 2018
Xian Wang, Haijiao Liu, Min Zhu, Changhong Cao, Zhensong Xu, Y. Tsatskis, Kimberly Lau, Chikin Kuok, T. Filleter, H. McNeill, C. Simmons, S. Hopyan, Yu Sun   +12 more
semanticscholar   +1 more source

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source

Disulfidptosis mechanisms and therapeutic implications in cancer metabolic reprogramming and future perspectives. [PDF]

Discov Oncol
Chen R, You J, Weng S, Zhao T.
europepmc   +1 more source

Physiological pH Transition‐Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles

Advanced Science, EarlyView.
Physiological pH transitions modulate protein corona dynamics on nanoparticles, altering their cellular uptake and inflammatory responses. Acidic pHs enhance protein adsorption, induce structural changes, and promote cellular uptake. Simultaneously, inflammatory responses are reduced due to altered protein composition, including decreased ...
Yuting Ge, Fangqin Fu, Yu Gao, Tianchang He, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +7 more
wiley   +1 more source

miRNAs and exosomes in psoriasis: coordinating cytoskeleton dynamics and extracellular matrix remodeling. [PDF]

Front Cell Dev Biol
Li S, Chik Z, Faruqu FN, Mohd Hashim N, Mohd Yusof NS, Fernandez Alarcon J, Ahmad N.   +6 more
europepmc   +1 more source

Involvement of a p53-independent and post-transcriptional up-regulation for p21WAF/CIP1 following destabilization of the actin cytoskeleton

, 1992
Yi Jang Lee, Cheng Han Tsai, Jeng Jong Hwang, Shu Jun Chiu, Tzong J. Sheu, Peter C. Keng   +5 more
openalex   +2 more sources

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

Advanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu, Huitong Ruan, Xiaolin Zhang, Weihan Zheng, Muhetaierjiang Mutailifu, Ling Wang, Liu Yu, Ruijun Peng, Rui Zhao, Zihan Wang, Jie Xu, Shaochuan Li, Yaobin Wu, Wenguo Cui, Mujun Lu   +14 more
wiley   +1 more source

Microtubules in the coenocyte Phytophthora function in nuclear positioning and sustaining tip growth

Kasteel M, Kots K, van den Hoogen J, Evangelisti E, Govers F, Ketelaar T.   +5 more
europepmc   +1 more source

A phenotypic screen for novel small molecules that correct tau-mediated pathologies in human frontotemporal dementia neurons. [PDF]

Alzheimers Dement
Maxwell H, Smith J, Campbell T, Clark J, La Rocca R, Paonessa F, Sitnikov S, Evans M, Maycox P, Livesey FJ.   +9 more
europepmc   +1 more source

Interaction of pp60c-src, phospholipase C, inositol-lipid, and diacyglycerol kinases with the cytoskeletons of thrombin-stimulated platelets

, 1991
Pascal Grondin, Monique Plantavid, Claire Racaud‐Sultan, M Breton, Gérard Mauco, Hugues Chap   +5 more
openalex   +1 more source