Results 311 to 320 of about 560,464 (384)

Progerin regulates actin cytoskeletal remodeling and inhibits EMT and metastasis in triple‑negative breast cancer cells. [PDF]

Int J Oncol
Huang X, Luo W, Liu W, Liu X, Chen W.
europepmc   +1 more source

Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes

, 2017
Swathi Ayloo, Pedro Guedes-Dias, Amy E. Ghiretti, Erika L.F. Holzbaur   +3 more
openalex   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Mechanical Properties of Endothelial Cells: A Key to Physiology, Drug Testing and Nanostructure Interaction. [PDF]

Cells
Kołodziejczyk AM, Kołodziejczyk Ł, Karwowski B.   +2 more
europepmc   +1 more source

Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow

Advanced Science, EarlyView.
DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley   +1 more source

CKAP4 Promotes Atrial Fibrosis and Enhances Atrial Fibrillation Vulnerability via WNT/β-Catenin Activation. [PDF]

Circ Arrhythm Electrophysiol
Feng Y, Chen Z, Gao Y, Liu X, Tan H.
europepmc   +1 more source

Mechanical Cues Regulate Cargo Sorting and Export at the Golgi

Advanced Science, EarlyView.
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino, Stefania Forciniti, Edoardo Scarpa, Antonio Ranieri, Lucia Santorelli, Gabriella De Blasi, Sara Costantini, Eunjoo Jun Lee, Antonio Galeone, Alessia Calcagnì, Marinella Pirozzi, Loretta L. del Mercato, Rossella Venditti, Giovanni D'Angelo, Seetharaman Parashuraman, Tiziano Verri, Giuseppe Gigli, Elizabeth S. Sztul, Paolo Grumati, Loris Rizzello, Domenico Russo, Riccardo Rizzo   +21 more
wiley   +1 more source

PRRSV promotes bacterial infection by remodeling actin cytoskeleton and cell membrane proteins. [PDF]

mBio
Liu X, Lv F, Zhu Y, Meng Y, Peng B, Zheng Z, Li Y, Xu L, Feng Y, Zhang J, Xiao S.   +10 more
europepmc   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

The septin cytoskeleton is a regulator of intestinal epithelial barrier integrity and mucosal inflammation. [PDF]

JCI Insight
Naydenov NG, Hu G, Robak D, Zafar A, Makhmudova K, Lechuga S, Ohno Y, Sangwan N, Bandyopadhyay S, Musich R, Jeffery E, Sun L, Marino-Melendez A, Rieder F, Sheynkman G, Ivanov AI, Ebrahim S.   +16 more
europepmc   +1 more source